STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glgCGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (381 aa)    
Predicted Functional Partners:
glgA
Glycogen synthase / GT5, similar to LACPI-0558 from L. piscium MKFS47; Synthesizes alpha-1,4-glucan chains using ADP-glucose.
 
 0.999
glgD
Putative glycogen biosynthesis protein GlgD,glucose-1-phosphate adenylyltransferase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
0.997
glgB
1,4-alpha-glucan branching enzyme GlgB / GH13, CBM48, similar to LACPI-0555 from L. piscium MKFS47; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.994
glgP
Glycogen phosphorylase / GT35, similar to LACPI-0559 from L. piscium MKFS47; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
 
 
 0.994
pgcA
Phosphoglucomutase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.936
gtfA
Sucrose phosphorylase / GH13, similar to LACPI-1289 from L. piscium MKFS47; Function of strongly homologous gene; enzyme.
  
 
 0.915
galU
UTP-glucose-1-phosphate uridylyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
0.913
apu
Putative Amylopullulanase (Includes: Alpha-amylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
  
 0.710
argG
Argininosuccinate synthase; Homologs of previously reported genes of unknown function;conserved hypothetical protein (containing DegV: EDD domain protein, DegV family) fragment 1; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
  
 0.645
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
  
  
 0.618
Your Current Organism:
Lactococcus piscium
NCBI taxonomy Id: 1364
Other names: ATCC 700018, CCUG 32207, CCUG 32732, CIP 104371, DSM 6634, JCM 11055, L. piscium, NCFB 2778, NCIMB 13196, strain HRIA 68
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