STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdhBPyruvate dehydrogenase (E1 beta subunit); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (326 aa)    
Predicted Functional Partners:
pdhA
Pyruvate dehydrogenase E1 component subunit alpha; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 0.999
pdhC
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 0.998
pdhD
Dihydrolipoyl dehydrogenase; Function of strongly homologous gene; enzyme.
 
 0.998
acoA
Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 0.996
nifJ
Pyruvate-flavodoxin oxidoreductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.962
pfl
Formate C-acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 
 0.930
pyk
Pyruvate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the pyruvate kinase family.
  
 
 0.920
pyc
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 
 0.920
ldhA
L-lactate dehydrogenase 1; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 0.918
SCA92666.1
Putative L-2-hydroxyisocaproate dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 0.918
Your Current Organism:
Lactococcus piscium
NCBI taxonomy Id: 1364
Other names: ATCC 700018, CCUG 32207, CCUG 32732, CIP 104371, DSM 6634, JCM 11055, L. piscium, NCFB 2778, NCIMB 13196, strain HRIA 68
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