node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
esxA | ylxM | LP2241_50195 | LP2241_30169 | Conserved hypothetical protein, virulence factor Type VII secretion system ESAT-6-like domain; Homologs of previously reported genes of unknown function; Belongs to the WXG100 family. | Conserved hypothetical protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. | 0.596 |
fbpA | mrnC | LP2241_30390 | LP2241_20244 | Fibronectin/fibrinogen-binding protein; Function of homologous gene experimentally demonstrated in an other organism; factor. | Mini-ribonuclease 3; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family. | 0.632 |
fbpA | trmK | LP2241_30390 | LP2241_30038 | Fibronectin/fibrinogen-binding protein; Function of homologous gene experimentally demonstrated in an other organism; factor. | tRNA (adenine(22)-N(1))-methyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.406 |
fbpA | ybeA | LP2241_30390 | LP2241_10304 | Fibronectin/fibrinogen-binding protein; Function of homologous gene experimentally demonstrated in an other organism; factor. | Conserved hypothetical protein(UPF0297 protein); Homologs of previously reported genes of unknown function; Belongs to the UPF0297 family. | 0.510 |
fbpA | ylxM | LP2241_30390 | LP2241_30169 | Fibronectin/fibrinogen-binding protein; Function of homologous gene experimentally demonstrated in an other organism; factor. | Conserved hypothetical protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. | 0.551 |
ffh | rsmB | LP2241_30170 | LP2241_50435 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.474 |
ffh | ylxM | LP2241_30170 | LP2241_30169 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Conserved hypothetical protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. | 0.911 |
mrnC | fbpA | LP2241_20244 | LP2241_30390 | Mini-ribonuclease 3; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family. | Fibronectin/fibrinogen-binding protein; Function of homologous gene experimentally demonstrated in an other organism; factor. | 0.632 |
mrnC | trmK | LP2241_20244 | LP2241_30038 | Mini-ribonuclease 3; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family. | tRNA (adenine(22)-N(1))-methyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.534 |
mrnC | whiA | LP2241_20244 | LP2241_30344 | Mini-ribonuclease 3; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family. | Putative sporulation transcription regulator WhiA; Involved in cell division and chromosome segregation. | 0.474 |
mrnC | ybeA | LP2241_20244 | LP2241_10304 | Mini-ribonuclease 3; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family. | Conserved hypothetical protein(UPF0297 protein); Homologs of previously reported genes of unknown function; Belongs to the UPF0297 family. | 0.610 |
mrnC | ygjB | LP2241_20244 | LP2241_20200 | Mini-ribonuclease 3; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.436 |
mrnC | ylxM | LP2241_20244 | LP2241_30169 | Mini-ribonuclease 3; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family. | Conserved hypothetical protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. | 0.598 |
rsmB | ffh | LP2241_50435 | LP2241_30170 | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.474 |
rsmB | ylxM | LP2241_50435 | LP2241_30169 | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Conserved hypothetical protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. | 0.568 |
trmK | fbpA | LP2241_30038 | LP2241_30390 | tRNA (adenine(22)-N(1))-methyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Fibronectin/fibrinogen-binding protein; Function of homologous gene experimentally demonstrated in an other organism; factor. | 0.406 |
trmK | mrnC | LP2241_30038 | LP2241_20244 | tRNA (adenine(22)-N(1))-methyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Mini-ribonuclease 3; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family. | 0.534 |
trmK | whiA | LP2241_30038 | LP2241_30344 | tRNA (adenine(22)-N(1))-methyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Putative sporulation transcription regulator WhiA; Involved in cell division and chromosome segregation. | 0.636 |
trmK | ybeA | LP2241_30038 | LP2241_10304 | tRNA (adenine(22)-N(1))-methyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Conserved hypothetical protein(UPF0297 protein); Homologs of previously reported genes of unknown function; Belongs to the UPF0297 family. | 0.707 |
trmK | ygjB | LP2241_30038 | LP2241_20200 | tRNA (adenine(22)-N(1))-methyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.532 |