STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lspALipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. (152 aa)    
Predicted Functional Partners:
rluD
Pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
  
    0.860
lgt
Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
 
   
 0.668
adcR
Transcriptional repressor AdcR; Function of homologous gene experimentally demonstrated in an other organism; regulator.
      
 0.655
kdpE
DNA-binding response regulator in two-component regulatory system with KdpD; Function of homologous gene experimentally demonstrated in an other organism; regulator.
 
   
 0.580
ileS
Isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
  
  
 0.570
aggL
Aggregation-promoting protein (modular protein); Function experimentally demonstrated in the studied genus; factor.
     
 0.543
pheT
Phenylalanine--tRNA ligase beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
 
    0.508
SCA92134.1
Putative two-component sensor histidine kinase KdpD; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
     
 0.497
manP
Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
 0.466
fruA-2
PTS system protein fructose specific IIA component; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
 0.466
Your Current Organism:
Lactococcus piscium
NCBI taxonomy Id: 1364
Other names: ATCC 700018, CCUG 32207, CCUG 32732, CIP 104371, DSM 6634, JCM 11055, L. piscium, NCFB 2778, NCIMB 13196, strain HRIA 68
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