STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mgfKGluconeogenesis morphogenetic factor; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. (325 aa)    
Predicted Functional Partners:
SCA92154.1
Putative GTPase; Displays ATPase and GTPase activities.
  
  
 0.943
whiA
Putative sporulation transcription regulator WhiA; Involved in cell division and chromosome segregation.
  
  
 0.918
SCA92155.1
Conserved membrane hypothetical protein; Homologs of previously reported genes of unknown function.
       0.773
SCA92157.1
Conserved hypothetical protein (containing a Acyl-ACP thioesterase); Homologs of previously reported genes of unknown function.
       0.762
yutF
Putative p-nitrophenyl phosphatase (YutF); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.757
topA
DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
   0.637
SCA92158.1
Putative lysozyme; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.610
phpP
Protein phosphatase PhpP; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
  
 0.580
brpA
Biofilm regulatory protein A; Function of homologous gene experimentally demonstrated in an other organism; regulator.
  
     0.549
hemN
Oxygen-independent coproporphyrinogen-III oxidase 1; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
       0.515
Your Current Organism:
Lactococcus piscium
NCBI taxonomy Id: 1364
Other names: ATCC 700018, CCUG 32207, CCUG 32732, CIP 104371, DSM 6634, JCM 11055, L. piscium, NCFB 2778, NCIMB 13196, strain HRIA 68
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