STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
msmR2Putative sucrose operon repressor (ScrR); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (324 aa)    
Predicted Functional Partners:
gltB-2
Glutamate synthase, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
 
 0.653
msmE2
Putative extracellular substrate-binding protein (MsmE); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative cell process.
 
  
 0.613
ptsH
Histidine-containing phosphocarrier protein of the phosphotransferase system (PTS); Function of homologous gene experimentally demonstrated in an other organism; factor.
   
 
 0.580
rbsK
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
 
  
 0.536
SCA92340.1
Transcriptional regulator, PadR family; Function of strongly homologous gene; regulator.
  
    0.502
cscA
Sucrose-6-phosphate hydrolase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family.
 
  
 0.499
SCA92338.1
Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function.
       0.486
SCA92339.1
Conserved membrane hypothetical protein; Homologs of previously reported genes of unknown function.
       0.486
guaA
GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP.
    
   0.455
metG
Methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
    
   0.428
Your Current Organism:
Lactococcus piscium
NCBI taxonomy Id: 1364
Other names: ATCC 700018, CCUG 32207, CCUG 32732, CIP 104371, DSM 6634, JCM 11055, L. piscium, NCFB 2778, NCIMB 13196, strain HRIA 68
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