| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SCA92929.1 | guaA | LP2241_50508 | LP2241_30320 | Putative tRNA binding domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | 0.489 |
| SCA92929.1 | pheS | LP2241_50508 | LP2241_50063 | Putative tRNA binding domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | Phenylalanine tRNA synthetase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | 0.850 |
| fusA | guaA | LP2241_50545 | LP2241_30320 | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | 0.738 |
| fusA | metG | LP2241_50545 | LP2241_40045 | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] | Methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | 0.462 |
| fusA | pheS | LP2241_50545 | LP2241_50063 | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] | Phenylalanine tRNA synthetase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | 0.699 |
| fusA | pheT | LP2241_50545 | LP2241_50062 | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] | Phenylalanine--tRNA ligase beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.457 |
| fusA | rplE | LP2241_50545 | LP2241_10238 | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] | 50S ribosomal subunit protein L5 (BL6); This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. | 0.993 |
| fusA | rpoA | LP2241_50545 | LP2241_10250 | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] | RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.934 |
| fusA | thrS | LP2241_50545 | LP2241_20260 | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] | Threonine--tRNA ligase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). | 0.675 |
| guaA | SCA92929.1 | LP2241_30320 | LP2241_50508 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Putative tRNA binding domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.489 |
| guaA | fusA | LP2241_30320 | LP2241_50545 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] | 0.738 |
| guaA | metG | LP2241_30320 | LP2241_40045 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | 0.870 |
| guaA | pheS | LP2241_30320 | LP2241_50063 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Phenylalanine tRNA synthetase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | 0.640 |
| guaA | pheT | LP2241_30320 | LP2241_50062 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Phenylalanine--tRNA ligase beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.924 |
| guaA | rplE | LP2241_30320 | LP2241_10238 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | 50S ribosomal subunit protein L5 (BL6); This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. | 0.490 |
| guaA | rpoA | LP2241_30320 | LP2241_10250 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.882 |
| guaA | thrS | LP2241_30320 | LP2241_20260 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Threonine--tRNA ligase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). | 0.700 |
| hisK | pheS | LP2241_50061 | LP2241_50063 | Histidinol-phosphatase; Function of strongly homologous gene; enzyme; Belongs to the PHP hydrolase family. HisK subfamily. | Phenylalanine tRNA synthetase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | 0.667 |
| hisK | pheT | LP2241_50061 | LP2241_50062 | Histidinol-phosphatase; Function of strongly homologous gene; enzyme; Belongs to the PHP hydrolase family. HisK subfamily. | Phenylalanine--tRNA ligase beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.704 |
| metG | fusA | LP2241_40045 | LP2241_50545 | Methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] | 0.462 |