STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
tpxPutative thiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. (159 aa)    
Predicted Functional Partners:
sodA
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.642
pgi
Glucose-6-phosphate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the GPI family.
  
  
 0.624
trxA
Thioredoxin; Function of homologous gene experimentally demonstrated in an other organism; carrier; Belongs to the thioredoxin family.
  
 
 0.577
pepT
Peptidase T(tripeptidase); Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.
   
    0.516
ahpC
Alkyl hydroperoxide reductase, C22 subunit; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
  
  
 0.495
gshB
Glutathione synthase (Glutathione synthase) (GSH synthetase) (GSH-S) (GSHase) (GS); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
 0.483
trxB
Thioredoxin reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
 0.480
mntR
Putative Mn-dependent transcriptional regulator MntR; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
  
  
 0.464
SCA92914.1
Putative Oxidoreductase, short-chain dehydrogenase/reductase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
    0.463
frr
Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.
  
 
 0.449
Your Current Organism:
Lactococcus piscium
NCBI taxonomy Id: 1364
Other names: ATCC 700018, CCUG 32207, CCUG 32732, CIP 104371, DSM 6634, JCM 11055, L. piscium, NCFB 2778, NCIMB 13196, strain HRIA 68
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