STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glaGlycerol facilitator-aquaporin gla; Function experimentally demonstrated in the studied genus; transporter; Belongs to the MIP/aquaporin (TC 1.A.8) family. (300 aa)    
Predicted Functional Partners:
glpO
Alpha-glycerophosphate oxidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.662
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
  
 
 0.635
SCA91165.1
Oxidoreductase; Function of strongly homologous gene; enzyme.
   
 
 0.607
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
    
 
 0.595
SCA92883.1
Conserved hypothetical protein, cyclic nucleotide-binding domain; Homologs of previously reported genes of unknown function.
   
 0.587
phpP
Protein phosphatase PhpP; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
 
 0.578
SCA90874.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
    
 
 0.476
ysaA
Putative hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
   
 
 0.455
yfnB
Putative nucleotidase (hydrolase activity); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
   
 
 0.455
SCA91746.1
Putative Glycerophosphoryl diester phosphodiesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.439
Your Current Organism:
Lactococcus piscium
NCBI taxonomy Id: 1364
Other names: ATCC 700018, CCUG 32207, CCUG 32732, CIP 104371, DSM 6634, JCM 11055, L. piscium, NCFB 2778, NCIMB 13196, strain HRIA 68
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