| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SCA91916.1 | phoH | LP2241_30105 | LP2241_50329 | Ferredoxin--NADP reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Phosphate starvation-inducible protein PhoH; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme;putative diadenosine tetraphosphate hydrolase (fragment), related HIT family hydrolase. | 0.584 |
| SCA92753.1 | obg | LP2241_50330 | LP2241_50331 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | GTPase involved in cell partitioning and DNA repair; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.659 |
| SCA92753.1 | phoH | LP2241_50330 | LP2241_50329 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Phosphate starvation-inducible protein PhoH; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme;putative diadenosine tetraphosphate hydrolase (fragment), related HIT family hydrolase. | 0.773 |
| cdd | era | LP2241_30519 | LP2241_20094 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.709 |
| cdd | phoH | LP2241_30519 | LP2241_50329 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Phosphate starvation-inducible protein PhoH; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme;putative diadenosine tetraphosphate hydrolase (fragment), related HIT family hydrolase. | 0.498 |
| cdd | ykjF | LP2241_30519 | LP2241_50326 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Endoribonuclease; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.422 |
| cmk | era | LP2241_30478 | LP2241_20094 | Cytidylate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.427 |
| cmk | phoH | LP2241_30478 | LP2241_50329 | Cytidylate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Phosphate starvation-inducible protein PhoH; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme;putative diadenosine tetraphosphate hydrolase (fragment), related HIT family hydrolase. | 0.539 |
| cmk | rsfS | LP2241_30478 | LP2241_10113 | Cytidylate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Ribosomal silencing factor RsfS; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.508 |
| cmk | rsmB | LP2241_30478 | LP2241_50435 | Cytidylate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.532 |
| era | cdd | LP2241_20094 | LP2241_30519 | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.709 |
| era | cmk | LP2241_20094 | LP2241_30478 | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Cytidylate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.427 |
| era | obg | LP2241_20094 | LP2241_50331 | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | GTPase involved in cell partitioning and DNA repair; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.426 |
| era | phoH | LP2241_20094 | LP2241_50329 | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Phosphate starvation-inducible protein PhoH; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme;putative diadenosine tetraphosphate hydrolase (fragment), related HIT family hydrolase. | 0.568 |
| era | recO | LP2241_20094 | LP2241_10050 | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.809 |
| era | rsmB | LP2241_20094 | LP2241_50435 | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.588 |
| era | ykjF | LP2241_20094 | LP2241_50326 | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Endoribonuclease; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.697 |
| obg | SCA92753.1 | LP2241_50331 | LP2241_50330 | GTPase involved in cell partitioning and DNA repair; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.659 |
| obg | era | LP2241_50331 | LP2241_20094 | GTPase involved in cell partitioning and DNA repair; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.426 |
| obg | phoH | LP2241_50331 | LP2241_50329 | GTPase involved in cell partitioning and DNA repair; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Phosphate starvation-inducible protein PhoH; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme;putative diadenosine tetraphosphate hydrolase (fragment), related HIT family hydrolase. | 0.653 |