STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCA92810.1Putative Secreted protein, function in cell-wall metabolism (Amidase) / CBM50; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (411 aa)    
Predicted Functional Partners:
FtsX
Cell division protein FtsX; Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
 
  
 0.718
SCA90959.1
Putative Muramidase-2 / CBM50, CBM50, CBM50, similar to LACPI-0102 from L. piscium MKFS47; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
  
0.716
SCA93050.1
CHAP domain-containing surface protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
     0.678
mreD
Conserved hypothetical protein containing Rod shape-determining protein MreD domain; Homologs of previously reported genes of unknown function.
     
 0.646
topA
DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
      
 0.641
ftsE-2
Cell division protein with ftsX, ATP-binding; Part of the ABC transporter FtsEX involved in cellular division.
 
  
 0.615
rpsA
30S Ribosomal protein S1; Function of homologous gene experimentally demonstrated in an other organism; factor.
   
  
 0.577
SCA90941.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
     0.531
ezrA
Septation ring formation regulator EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family.
  
    0.523
pvaA
Lysozyme-like protein; Function of strongly homologous gene; enzyme.
 
   
 0.509
Your Current Organism:
Lactococcus piscium
NCBI taxonomy Id: 1364
Other names: ATCC 700018, CCUG 32207, CCUG 32732, CIP 104371, DSM 6634, JCM 11055, L. piscium, NCFB 2778, NCIMB 13196, strain HRIA 68
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