| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SCA92830.1 | SCA92831.1 | LP2241_50408 | LP2241_50409 | Putative transcriptional regulator Rrf2-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. | Putative membrane transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | 0.471 |
| SCA92831.1 | SCA92830.1 | LP2241_50409 | LP2241_50408 | Putative membrane transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | Putative transcriptional regulator Rrf2-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. | 0.471 |
| SCA92831.1 | mtnN | LP2241_50409 | LP2241_50414 | Putative membrane transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. | 0.438 |
| SCA92831.1 | nadD-2 | LP2241_50409 | LP2241_50411 | Putative membrane transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.437 |
| SCA92831.1 | nadE | LP2241_50409 | LP2241_50412 | Putative membrane transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | NAD synthetase, NH3/glutamine-dependent; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | 0.459 |
| SCA92831.1 | pepC | LP2241_50409 | LP2241_50410 | Putative membrane transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | Function experimentally demonstrated in the studied genus; enzyme; Belongs to the peptidase C1 family. | 0.492 |
| SCA92831.1 | pncB | LP2241_50409 | LP2241_50413 | Putative membrane transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.445 |
| mtnN | SCA92831.1 | LP2241_50414 | LP2241_50409 | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. | Putative membrane transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | 0.438 |
| mtnN | nadD-2 | LP2241_50414 | LP2241_50411 | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.800 |
| mtnN | nadE | LP2241_50414 | LP2241_50412 | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. | NAD synthetase, NH3/glutamine-dependent; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | 0.861 |
| mtnN | pepC | LP2241_50414 | LP2241_50410 | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. | Function experimentally demonstrated in the studied genus; enzyme; Belongs to the peptidase C1 family. | 0.694 |
| mtnN | pncB | LP2241_50414 | LP2241_50413 | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.774 |
| nadD-2 | SCA92831.1 | LP2241_50411 | LP2241_50409 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Putative membrane transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | 0.437 |
| nadD-2 | mtnN | LP2241_50411 | LP2241_50414 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. | 0.800 |
| nadD-2 | nadE | LP2241_50411 | LP2241_50412 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | NAD synthetase, NH3/glutamine-dependent; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | 0.942 |
| nadD-2 | pepC | LP2241_50411 | LP2241_50410 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Function experimentally demonstrated in the studied genus; enzyme; Belongs to the peptidase C1 family. | 0.675 |
| nadD-2 | pncB | LP2241_50411 | LP2241_50413 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.940 |
| nadE | SCA92831.1 | LP2241_50412 | LP2241_50409 | NAD synthetase, NH3/glutamine-dependent; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | Putative membrane transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | 0.459 |
| nadE | mtnN | LP2241_50412 | LP2241_50414 | NAD synthetase, NH3/glutamine-dependent; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. | 0.861 |
| nadE | nadD-2 | LP2241_50412 | LP2241_50411 | NAD synthetase, NH3/glutamine-dependent; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.942 |