| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| acoB | pdhC | LP2241_30044 | LP2241_20389 | Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit beta; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.989 |
| acoB | phpP | LP2241_30044 | LP2241_50434 | Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit beta; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Protein phosphatase PhpP; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.606 |
| dnaJ | gla | LP2241_10105 | LP2241_50211 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Glycerol facilitator-aquaporin gla; Function experimentally demonstrated in the studied genus; transporter; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.595 |
| dnaJ | glpF | LP2241_10105 | LP2241_30162 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Glycerol uptake facilitator protein; Function of homologous gene experimentally demonstrated in an other organism; transporter; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.595 |
| dnaJ | phpP | LP2241_10105 | LP2241_50434 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Protein phosphatase PhpP; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.632 |
| dnaJ | pknB | LP2241_10105 | LP2241_50433 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Serine/threonine-protein kinase PknB; Function of strongly homologous gene; enzyme. | 0.405 |
| fmt | phpP | LP2241_50436 | LP2241_50434 | Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Protein phosphatase PhpP; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.883 |
| fmt | pknB | LP2241_50436 | LP2241_50433 | Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Serine/threonine-protein kinase PknB; Function of strongly homologous gene; enzyme. | 0.503 |
| fmt | rsmB | LP2241_50436 | LP2241_50435 | Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.999 |
| gla | dnaJ | LP2241_50211 | LP2241_10105 | Glycerol facilitator-aquaporin gla; Function experimentally demonstrated in the studied genus; transporter; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.595 |
| gla | phpP | LP2241_50211 | LP2241_50434 | Glycerol facilitator-aquaporin gla; Function experimentally demonstrated in the studied genus; transporter; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Protein phosphatase PhpP; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.578 |
| glpF | dnaJ | LP2241_30162 | LP2241_10105 | Glycerol uptake facilitator protein; Function of homologous gene experimentally demonstrated in an other organism; transporter; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.595 |
| glpF | phpP | LP2241_30162 | LP2241_50434 | Glycerol uptake facilitator protein; Function of homologous gene experimentally demonstrated in an other organism; transporter; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Protein phosphatase PhpP; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.578 |
| mgfK | phpP | LP2241_30345 | LP2241_50434 | Gluconeogenesis morphogenetic factor; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | Protein phosphatase PhpP; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.580 |
| pdhB | pdhC | LP2241_20388 | LP2241_20389 | Pyruvate dehydrogenase (E1 beta subunit); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.998 |
| pdhB | phpP | LP2241_20388 | LP2241_50434 | Pyruvate dehydrogenase (E1 beta subunit); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Protein phosphatase PhpP; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.606 |
| pdhC | acoB | LP2241_20389 | LP2241_30044 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit beta; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.989 |
| pdhC | pdhB | LP2241_20389 | LP2241_20388 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Pyruvate dehydrogenase (E1 beta subunit); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.998 |
| pdhC | phpP | LP2241_20389 | LP2241_50434 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Protein phosphatase PhpP; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.613 |
| phpP | acoB | LP2241_50434 | LP2241_30044 | Protein phosphatase PhpP; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit beta; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.606 |