STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCA92884.1Conserved membrane hypothetical protein; Homologs of previously reported genes of unknown function. (173 aa)    
Predicted Functional Partners:
mprF
Putative lysylphosphatidylglycerol synthetase/glycosyltransferase; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
 
     0.496
SCA91229.1
Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function.
  
     0.482
spxA-2
Regulatory protein spx, thioredoxine like; Function experimentally demonstrated in the studied genus; regulator; Belongs to the ArsC family.
  
    0.471
SCA91225.1
Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function.
  
    0.410
SCA91230.1
Exported hypothetical protein; No homology to any previously reported sequences.
  
     0.405
SCA91001.1
Cell surface hypothetical protein; No homology to any previously reported sequences.
  
     0.400
Your Current Organism:
Lactococcus piscium
NCBI taxonomy Id: 1364
Other names: ATCC 700018, CCUG 32207, CCUG 32732, CIP 104371, DSM 6634, JCM 11055, L. piscium, NCFB 2778, NCIMB 13196, strain HRIA 68
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