| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SCA92909.1 | nifS | LP2241_50488 | LP2241_50490 | Putative multidrug resitance protein, Permease of the major facilitator superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | Putative cysteine desulfurase (IscS); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.610 |
| SCA92909.1 | thiI | LP2241_50488 | LP2241_50489 | Putative multidrug resitance protein, Permease of the major facilitator superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.737 |
| guaA | tadA | LP2241_30320 | LP2241_30411 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.517 |
| guaA | thiI | LP2241_30320 | LP2241_50489 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.413 |
| iscS | nifS | LP2241_20238 | LP2241_50490 | Cysteine desulfurase IscS; Function of strongly homologous gene; enzyme. | Putative cysteine desulfurase (IscS); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.916 |
| iscS | thiI | LP2241_20238 | LP2241_50489 | Cysteine desulfurase IscS; Function of strongly homologous gene; enzyme. | tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.962 |
| mnmA | rsmB | LP2241_20447 | LP2241_50435 | tRNA 2-thiouridylase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.537 |
| mnmA | thiI | LP2241_20447 | LP2241_50489 | tRNA 2-thiouridylase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.451 |
| nifS | SCA92909.1 | LP2241_50490 | LP2241_50488 | Putative cysteine desulfurase (IscS); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative multidrug resitance protein, Permease of the major facilitator superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | 0.610 |
| nifS | iscS | LP2241_50490 | LP2241_20238 | Putative cysteine desulfurase (IscS); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Cysteine desulfurase IscS; Function of strongly homologous gene; enzyme. | 0.916 |
| nifS | thiI | LP2241_50490 | LP2241_50489 | Putative cysteine desulfurase (IscS); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.991 |
| queA | rsmB | LP2241_30548 | LP2241_50435 | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.554 |
| queA | thiI | LP2241_30548 | LP2241_50489 | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.416 |
| rsmB | mnmA | LP2241_50435 | LP2241_20447 | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | tRNA 2-thiouridylase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.537 |
| rsmB | queA | LP2241_50435 | LP2241_30548 | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.554 |
| rsmB | tadA | LP2241_50435 | LP2241_30411 | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.464 |
| rsmB | thiI | LP2241_50435 | LP2241_50489 | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.955 |
| tadA | guaA | LP2241_30411 | LP2241_30320 | tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | 0.517 |
| tadA | rsmB | LP2241_30411 | LP2241_50435 | tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.464 |
| tadA | thiI | LP2241_30411 | LP2241_50489 | tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.560 |