STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LP2241_60030Homologs of previously reported genes of unknown function;fragment of conserved hypothetical protein (part 2). (827 aa)    
Predicted Functional Partners:
SCA93039.1
Conserved hypothetical protein containing replication factor; Homologs of previously reported genes of unknown function.
 
    0.775
LP2241_60027
Homologs of previously reported genes of unknown function;fragment of conserved hypothetical protein (part 1).
  
    0.659
SCA93037.1
Putative Ftsk domain-containing protein YdcQ; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
  
 0.612
pvaA
Lysozyme-like protein; Function of strongly homologous gene; enzyme.
 
   
 0.565
SCA91280.1
FtsK protein; Function of strongly homologous gene; factor.
 
  
 0.546
topA
DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.543
yesO
Putative Sugar transport system sugar-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
  
     0.497
LP2241_60032
Homologs of previously reported genes of unknown function;fragment of conserved hypothetical protein.
       0.480
SCA93050.1
CHAP domain-containing surface protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
 0.437
SCA92810.1
Putative Secreted protein, function in cell-wall metabolism (Amidase) / CBM50; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
  
 0.432
Your Current Organism:
Lactococcus piscium
NCBI taxonomy Id: 1364
Other names: ATCC 700018, CCUG 32207, CCUG 32732, CIP 104371, DSM 6634, JCM 11055, L. piscium, NCFB 2778, NCIMB 13196, strain HRIA 68
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