STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W6PU89_PENRFFolic acid synthesis protein. (465 aa)    
Predicted Functional Partners:
W6Q141_PENRF
Dihydrofolate synthetase; Belongs to the folylpolyglutamate synthase family.
  
 
 0.964
met-6
Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.
  
 
 0.947
W6QW14_PENRF
Folylpolyglutamate synthetase.
  
 
 0.947
W6Q005_PENRF
GTP cyclohydrolase I.
  
 
 0.939
W6QCZ5_PENRF
GTP cyclohydrolase I.
  
 
 0.939
W6Q601_PENRF
Aminotransferase, class IV.
     
 0.917
ADE3
C-1-tetrahydrofolate synthase, cytoplasmic.
    
 0.869
W6QL24_PENRF
Para-aminobenzoate synthase.
  
 
 0.834
TRP2
Anthranilate synthase component 1.
  
 
 0.787
trpC
Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.
  
  
 0.767
Your Current Organism:
Penicillium roqueforti
NCBI taxonomy Id: 1365484
Other names: P. roqueforti FM164, Penicillium roqueforti FM164
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