node1 | node2 | node1 annotation | node2 annotation | score |
SAMN05428963_101230 | SAMN05428963_104299 | 2-keto-4-pentenoate hydratase. | 4-hydroxy-4-methyl-2-oxoglutarate aldolase; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions. | 0.637 |
SAMN05428963_101230 | SAMN05428963_11859 | 2-keto-4-pentenoate hydratase. | Regulator of RNase E activity RraA. | 0.537 |
SAMN05428963_101230 | SAMN05428963_12233 | 2-keto-4-pentenoate hydratase. | Regulator of RNase E activity RraA. | 0.551 |
SAMN05428963_101288 | SAMN05428963_102248 | Oxaloacetate decarboxylase, alpha subunit. | Citrate lyase subunit beta / citryl-CoA lyase; Belongs to the HpcH/HpaI aldolase family. | 0.875 |
SAMN05428963_101288 | SAMN05428963_103366 | Oxaloacetate decarboxylase, alpha subunit. | Malate dehydrogenase (Oxaloacetate-decarboxylating)(NADP+). | 0.897 |
SAMN05428963_101288 | SAMN05428963_104205 | Oxaloacetate decarboxylase, alpha subunit. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.719 |
SAMN05428963_101288 | SAMN05428963_104299 | Oxaloacetate decarboxylase, alpha subunit. | 4-hydroxy-4-methyl-2-oxoglutarate aldolase; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions. | 0.730 |
SAMN05428963_101288 | SAMN05428963_11859 | Oxaloacetate decarboxylase, alpha subunit. | Regulator of RNase E activity RraA. | 0.720 |
SAMN05428963_101288 | SAMN05428963_12233 | Oxaloacetate decarboxylase, alpha subunit. | Regulator of RNase E activity RraA. | 0.720 |
SAMN05428963_101288 | SAMN05428963_12234 | Oxaloacetate decarboxylase, alpha subunit. | Malate/lactate/ureidoglycolate dehydrogenase, LDH2 family; Belongs to the LDH2/MDH2 oxidoreductase family. | 0.705 |
SAMN05428963_102248 | SAMN05428963_101288 | Citrate lyase subunit beta / citryl-CoA lyase; Belongs to the HpcH/HpaI aldolase family. | Oxaloacetate decarboxylase, alpha subunit. | 0.875 |
SAMN05428963_102248 | SAMN05428963_103366 | Citrate lyase subunit beta / citryl-CoA lyase; Belongs to the HpcH/HpaI aldolase family. | Malate dehydrogenase (Oxaloacetate-decarboxylating)(NADP+). | 0.865 |
SAMN05428963_102248 | SAMN05428963_104299 | Citrate lyase subunit beta / citryl-CoA lyase; Belongs to the HpcH/HpaI aldolase family. | 4-hydroxy-4-methyl-2-oxoglutarate aldolase; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions. | 0.422 |
SAMN05428963_102248 | SAMN05428963_11859 | Citrate lyase subunit beta / citryl-CoA lyase; Belongs to the HpcH/HpaI aldolase family. | Regulator of RNase E activity RraA. | 0.628 |
SAMN05428963_102248 | SAMN05428963_12233 | Citrate lyase subunit beta / citryl-CoA lyase; Belongs to the HpcH/HpaI aldolase family. | Regulator of RNase E activity RraA. | 0.629 |
SAMN05428963_103366 | SAMN05428963_101288 | Malate dehydrogenase (Oxaloacetate-decarboxylating)(NADP+). | Oxaloacetate decarboxylase, alpha subunit. | 0.897 |
SAMN05428963_103366 | SAMN05428963_102248 | Malate dehydrogenase (Oxaloacetate-decarboxylating)(NADP+). | Citrate lyase subunit beta / citryl-CoA lyase; Belongs to the HpcH/HpaI aldolase family. | 0.865 |
SAMN05428963_103366 | SAMN05428963_104205 | Malate dehydrogenase (Oxaloacetate-decarboxylating)(NADP+). | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.455 |
SAMN05428963_103366 | SAMN05428963_104215 | Malate dehydrogenase (Oxaloacetate-decarboxylating)(NADP+). | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | 0.445 |
SAMN05428963_103366 | SAMN05428963_104299 | Malate dehydrogenase (Oxaloacetate-decarboxylating)(NADP+). | 4-hydroxy-4-methyl-2-oxoglutarate aldolase; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions. | 0.740 |