STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AGW94374.13-methylcrotonyl-CoA carboxylase subunit alpha; K01958: PC, pyc; pyruvate carboxylase [EC:6.4.1.1]. (1167 aa)    
Predicted Functional Partners:
AGW89314.1
Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; K00029: E1.1.1.40, maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40].
   
 0.967
AGW91916.1
Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; K00029: E1.1.1.40, maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40].
   
 0.967
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.961
AGW93831.1
K00016: LDH, ldh; L-lactate dehydrogenase [EC:1.1.1.27].
  
 0.961
AGW92175.1
K00265: gltB; glutamate synthase (NADPH/NADH) large chain [EC:1.4.1.13 1.4.1.14].
  
 
 0.945
gltA
Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; K01647: CS, gltA; citrate synthase [EC:2.3.3.1].
  
 0.939
AGW93551.1
K01647: CS, gltA; citrate synthase [EC:2.3.3.1].
  
 0.939
AGW89026.1
Hypothetical protein.
 
  
0.936
AGW89025.1
Hypothetical protein.
 
  
0.934
lldD
Flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration; K00101: E1.1.2.3, lldD; L-lactate dehydrogenase (cytochrome) [EC:1.1.2.3].
  
 
 0.930
Your Current Organism:
Ralstonia pickettii DTP0602
NCBI taxonomy Id: 1366050
Other names: R. pickettii DTP0602
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