AYL99_09283 protein (Fonsecaea erecta) - STRING interaction network

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second shell of interactors

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

AYL99_09283

Uncharacterized protein. (1038 aa)

Predicted Functional Partners:

AYL99_11268

0.618

AYL99_06847

0.615

AYL99_06846

0.615

AYL99_04501

0.567

AYL99_09271

0.473

AYL99_06834

0.457

AYL99_08477

0.449

AYL99_04683

0.449

AYL99_04035

0.444

AYL99_02907

0.433

Your Current Organism:

Fonsecaea erecta

NCBI taxonomy Id: 1367422
Other names: F. erecta, Fonsecaea erecta V. A. Vicente, Najafzadeh, Sun & de Hoog 2013, Fonsecaea sp. RG-2013a

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AYL99_02907	AYL99_09283	A0A178ZV76	A0A178Z8I8	AMP deaminase.	Uncharacterized protein.	0.433
AYL99_04035	AYL99_04501	A0A178ZQA9	A0A178ZR32	SCA7 domain-containing protein.	Bromo domain-containing protein.	0.996
AYL99_04035	AYL99_06834	A0A178ZQA9	A0A178ZJG0	SCA7 domain-containing protein.	SANT domain-containing protein.	0.951
AYL99_04035	AYL99_09283	A0A178ZQA9	A0A178Z8I8	SCA7 domain-containing protein.	Uncharacterized protein.	0.444
AYL99_04035	AYL99_11268	A0A178ZQA9	A0A178Z4X8	SCA7 domain-containing protein.	Uncharacterized protein.	0.994
AYL99_04501	AYL99_04035	A0A178ZR32	A0A178ZQA9	Bromo domain-containing protein.	SCA7 domain-containing protein.	0.996
AYL99_04501	AYL99_06834	A0A178ZR32	A0A178ZJG0	Bromo domain-containing protein.	SANT domain-containing protein.	0.922
AYL99_04501	AYL99_09283	A0A178ZR32	A0A178Z8I8	Bromo domain-containing protein.	Uncharacterized protein.	0.567
AYL99_04501	AYL99_11268	A0A178ZR32	A0A178Z4X8	Bromo domain-containing protein.	Uncharacterized protein.	0.993
AYL99_04683	AYL99_09283	A0A178ZRM2	A0A178Z8I8	F-box domain-containing protein.	Uncharacterized protein.	0.449
AYL99_06834	AYL99_04035	A0A178ZJG0	A0A178ZQA9	SANT domain-containing protein.	SCA7 domain-containing protein.	0.951
AYL99_06834	AYL99_04501	A0A178ZJG0	A0A178ZR32	SANT domain-containing protein.	Bromo domain-containing protein.	0.922
AYL99_06834	AYL99_09283	A0A178ZJG0	A0A178Z8I8	SANT domain-containing protein.	Uncharacterized protein.	0.457
AYL99_06846	AYL99_06847	A0A178ZID5	A0A178ZIC1	NFACT-R_1 domain-containing protein.	Uncharacterized protein.	0.414
AYL99_06846	AYL99_09283	A0A178ZID5	A0A178Z8I8	NFACT-R_1 domain-containing protein.	Uncharacterized protein.	0.615
AYL99_06847	AYL99_06846	A0A178ZIC1	A0A178ZID5	Uncharacterized protein.	NFACT-R_1 domain-containing protein.	0.414
AYL99_06847	AYL99_09283	A0A178ZIC1	A0A178Z8I8	Uncharacterized protein.	Uncharacterized protein.	0.615
AYL99_08477	AYL99_09283	A0A178ZD88	A0A178Z8I8	Uncharacterized protein.	Uncharacterized protein.	0.449
AYL99_09271	AYL99_09283	A0A178Z8U2	A0A178Z8I8	Uncharacterized protein.	Uncharacterized protein.	0.473
AYL99_09283	AYL99_02907	A0A178Z8I8	A0A178ZV76	Uncharacterized protein.	AMP deaminase.	0.433

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Network Stats

number of nodes:

11

number of edges:

50

average node degree:

9.09

avg. local clustering coefficient:

0.934

expected number of edges:

16

PPI enrichment p-value:

1.74e-11

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006096

Glycolytic process

6 of 15

1.92

3.23

3.33e-08

GO:0006091

Generation of precursor metabolites and energy

10 of 72

1.46

2.7

2.09e-11

GO:0006098

Pentose-phosphate shunt

4 of 8

2.02

2.5

6.23e-06

GO:0006006

Glucose metabolic process

4 of 12

1.84

2.16

1.86e-05

GO:0005975

Carbohydrate metabolic process

9 of 110

1.23

1.71

3.33e-08

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1451

Glycolysis, and Glyceraldehyde-3-phosphate dehydrogenase, type I

8 of 11

2.18

5.58

1.72e-13

CL:1447

Pentose phosphate pathway, and Glycolysis

10 of 31

1.83

4.69

5.80e-15

CL:1453

Glyceraldehyde-3-phosphate dehydrogenase, type I, and Glycolysis

3 of 5

2.1

1.79

0.00031

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

nae01200

Carbon metabolism

11 of 81

1.45

2.95

2.33e-14

nae00030

Pentose phosphate pathway

5 of 16

1.81

2.75

2.91e-07

nae00010

Glycolysis / Gluconeogenesis

6 of 31

1.61

2.49

1.02e-07

nae00680

Methane metabolism

4 of 16

1.72

2.05

1.70e-05

nae01230

Biosynthesis of amino acids

9 of 101

1.27

1.92

1.63e-09

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0324

Glycolysis

6 of 8

2.19

4.19

1.23e-09

KW-0312

Gluconeogenesis

2 of 5

1.92

0.74

0.0401

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF02781

Glucose-6-phosphate dehydrogenase, C-terminal domain

2 of 2

2.32

0.74

0.0447

PF00479

Glucose-6-phosphate dehydrogenase, NAD binding domain

2 of 2

2.32

0.74

0.0447

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