AYL99_07623 protein (Fonsecaea erecta) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Score

AYL99_07623

DAO domain-containing protein. (276 aa)

Predicted Functional Partners:

AYL99_08301

0.738

AYL99_11186

0.626

AYL99_09822

0.626

AYL99_09028

0.626

AYL99_08258

0.626

AYL99_04958

0.626

AYL99_00482

0.626

AYL99_01297

0.626

AYL99_05385

0.612

AYL99_04147

0.612

Your Current Organism:

Fonsecaea erecta

NCBI taxonomy Id: 1367422
Other names: F. erecta, Fonsecaea erecta V. A. Vicente, Najafzadeh, Sun & de Hoog 2013, Fonsecaea sp. RG-2013a

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AYL99_00482	AYL99_04147	A0A178ZXF1	A0A178ZQ34	Rieske domain-containing protein.	Uncharacterized protein.	0.487
AYL99_00482	AYL99_04958	A0A178ZXF1	A0A178ZKM4	Rieske domain-containing protein.	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	0.487
AYL99_00482	AYL99_05385	A0A178ZXF1	A0A178ZME6	Rieske domain-containing protein.	Zn(2)-C6 fungal-type domain-containing protein.	0.487
AYL99_00482	AYL99_07623	A0A178ZXF1	A0A178ZH75	Rieske domain-containing protein.	DAO domain-containing protein.	0.626
AYL99_01297	AYL99_04147	A0A179A2F9	A0A178ZQ34	Pyr_redox_2 domain-containing protein.	Uncharacterized protein.	0.487
AYL99_01297	AYL99_04958	A0A179A2F9	A0A178ZKM4	Pyr_redox_2 domain-containing protein.	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	0.487
AYL99_01297	AYL99_05385	A0A179A2F9	A0A178ZME6	Pyr_redox_2 domain-containing protein.	Zn(2)-C6 fungal-type domain-containing protein.	0.487
AYL99_01297	AYL99_07623	A0A179A2F9	A0A178ZH75	Pyr_redox_2 domain-containing protein.	DAO domain-containing protein.	0.626
AYL99_04147	AYL99_00482	A0A178ZQ34	A0A178ZXF1	Uncharacterized protein.	Rieske domain-containing protein.	0.487
AYL99_04147	AYL99_01297	A0A178ZQ34	A0A179A2F9	Uncharacterized protein.	Pyr_redox_2 domain-containing protein.	0.487
AYL99_04147	AYL99_07623	A0A178ZQ34	A0A178ZH75	Uncharacterized protein.	DAO domain-containing protein.	0.612
AYL99_04147	AYL99_08258	A0A178ZQ34	A0A178ZCK0	Uncharacterized protein.	Zn(2)-C6 fungal-type domain-containing protein.	0.487
AYL99_04147	AYL99_08301	A0A178ZQ34	A0A178ZEF7	Uncharacterized protein.	Tryptophan synthase.	0.805
AYL99_04147	AYL99_09028	A0A178ZQ34	A0A178ZBR9	Uncharacterized protein.	Pyr_redox_2 domain-containing protein.	0.487
AYL99_04147	AYL99_09822	A0A178ZQ34	A0A178Z7B5	Uncharacterized protein.	Nitrite reductase [NAD(P)H], large subunit.	0.487
AYL99_04147	AYL99_11186	A0A178ZQ34	A0A178Z4Q4	Uncharacterized protein.	Pyr_redox_2 domain-containing protein.	0.487
AYL99_04958	AYL99_00482	A0A178ZKM4	A0A178ZXF1	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Rieske domain-containing protein.	0.487
AYL99_04958	AYL99_01297	A0A178ZKM4	A0A179A2F9	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Pyr_redox_2 domain-containing protein.	0.487
AYL99_04958	AYL99_07623	A0A178ZKM4	A0A178ZH75	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	DAO domain-containing protein.	0.626
AYL99_04958	AYL99_08258	A0A178ZKM4	A0A178ZCK0	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Zn(2)-C6 fungal-type domain-containing protein.	0.487

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Network Stats

number of nodes:

4

number of edges:

5

average node degree:

2.5

avg. local clustering coefficient:

0.833

expected number of edges:

3

PPI enrichment p-value:

0.157

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004129

Cytochrome-c oxidase activity

3 of 5

2.22

1.54

0.0012

GO:0005507

Copper ion binding

2 of 8

1.84

0.7

0.0465

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005886

Plasma membrane

8 of 410

0.74

0.58

0.0017

GO:0016021

Integral component of membrane

8 of 680

0.52

0.35

0.0233

GO:0016020

Membrane

9 of 975

0.41

0.29

0.0259

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:24804722

(2014) Evolution of mitochondria reconstructed from the energy metabolism of living bacteria.

2 of 2

2.44

1.5

0.0017

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2145

Copper, and Heme biosynthesis

7 of 7

2.44

5.78

1.58e-12

CL:2078

Oxidative phosphorylation, and Peptidase M16, C-terminal

9 of 42

1.78

4.0

1.58e-12

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

mmr00190

Oxidative phosphorylation

6 of 44

1.58

2.25

6.39e-07

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0186

Copper

3 of 3

2.44

2.06

0.00014

KW-0679

Respiratory chain

2 of 5

2.05

1.09

0.0086

KW-0350

Heme biosynthesis

2 of 5

2.05

1.09

0.0086

KW-1003

Cell membrane

5 of 140

1.0

0.76

0.0034

KW-1133

Transmembrane helix

9 of 581

0.63

0.5

0.0013

(more ...)

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