STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AYL99_03848BRCT domain-containing protein. (1382 aa)    
Predicted Functional Partners:
AYL99_05547
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
    
 0.988
AYL99_02324
Uncharacterized protein.
    
 
 0.988
AYL99_01924
Uncharacterized protein; Belongs to the protein kinase superfamily.
    
 0.981
AYL99_02482
Uncharacterized protein.
    
 0.981
AYL99_02042
Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily.
    
 0.979
AYL99_07769
Histone H2A; Belongs to the histone H2A family.
    
 0.972
AYL99_11425
Uncharacterized protein.
    
 0.961
AYL99_05885
Uncharacterized protein.
    
 0.961
AYL99_00283
Protein kinase domain-containing protein.
    
 
 0.953
AYL99_10614
Uncharacterized protein.
    
 0.942
Your Current Organism:
Fonsecaea erecta
NCBI taxonomy Id: 1367422
Other names: F. erecta, Fonsecaea erecta V. A. Vicente, Najafzadeh, Sun & de Hoog 2013, Fonsecaea sp. RG-2013a
Server load: low (28%) [HD]