AYL99_01824 protein (Fonsecaea erecta) - STRING interaction network

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second shell of interactors

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filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

AYL99_01824

Uncharacterized protein. (475 aa)

Predicted Functional Partners:

AYL99_11671

0.976

AYL99_11088

0.976

AYL99_11089

0.976

AYL99_06566

0.976

AYL99_02996

0.964

AYL99_05593

0.957

AYL99_04483

0.946

AYL99_10140

0.939

AYL99_09925

0.915

AYL99_01850

0.915

Your Current Organism:

Fonsecaea erecta

NCBI taxonomy Id: 1367422
Other names: F. erecta, Fonsecaea erecta V. A. Vicente, Najafzadeh, Sun & de Hoog 2013, Fonsecaea sp. RG-2013a

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AYL99_01824	AYL99_01850	A0A178ZS09	A0A178ZTV1	Uncharacterized protein.	Uncharacterized protein.	0.915
AYL99_01824	AYL99_02996	A0A178ZS09	A0A178ZVH7	Uncharacterized protein.	Polyubiquitin.	0.964
AYL99_01824	AYL99_04483	A0A178ZS09	A0A178ZR45	Uncharacterized protein.	Uncharacterized protein.	0.946
AYL99_01824	AYL99_05593	A0A178ZS09	A0A178ZM75	Uncharacterized protein.	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	0.957
AYL99_01824	AYL99_06566	A0A178ZS09	A0A178ZHL5	Uncharacterized protein.	Ubiquitin-conjugating enzyme E2 2; Belongs to the ubiquitin-conjugating enzyme family.	0.976
AYL99_01824	AYL99_09925	A0A178ZS09	A0A178Z9B0	Uncharacterized protein.	DNA polymerase.	0.915
AYL99_01824	AYL99_10140	A0A178ZS09	A0A178Z880	Uncharacterized protein.	Uncharacterized protein.	0.939
AYL99_01824	AYL99_11088	A0A178ZS09	A0A178Z4G5	Uncharacterized protein.	Vezatin domain-containing protein.	0.976
AYL99_01824	AYL99_11089	A0A178ZS09	A0A178Z548	Uncharacterized protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.976
AYL99_01824	AYL99_11671	A0A178ZS09	A0A178Z3S9	Uncharacterized protein.	Ubiquitin-conjugating enzyme E2 2; Belongs to the ubiquitin-conjugating enzyme family.	0.976
AYL99_01850	AYL99_01824	A0A178ZTV1	A0A178ZS09	Uncharacterized protein.	Uncharacterized protein.	0.915
AYL99_01850	AYL99_02996	A0A178ZTV1	A0A178ZVH7	Uncharacterized protein.	Polyubiquitin.	0.561
AYL99_01850	AYL99_04483	A0A178ZTV1	A0A178ZR45	Uncharacterized protein.	Uncharacterized protein.	0.947
AYL99_01850	AYL99_05593	A0A178ZTV1	A0A178ZM75	Uncharacterized protein.	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	0.951
AYL99_01850	AYL99_06566	A0A178ZTV1	A0A178ZHL5	Uncharacterized protein.	Ubiquitin-conjugating enzyme E2 2; Belongs to the ubiquitin-conjugating enzyme family.	0.713
AYL99_01850	AYL99_09925	A0A178ZTV1	A0A178Z9B0	Uncharacterized protein.	DNA polymerase.	0.852
AYL99_01850	AYL99_10140	A0A178ZTV1	A0A178Z880	Uncharacterized protein.	Uncharacterized protein.	0.612
AYL99_01850	AYL99_11088	A0A178ZTV1	A0A178Z4G5	Uncharacterized protein.	Vezatin domain-containing protein.	0.888
AYL99_01850	AYL99_11089	A0A178ZTV1	A0A178Z548	Uncharacterized protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.888
AYL99_01850	AYL99_11671	A0A178ZTV1	A0A178Z3S9	Uncharacterized protein.	Ubiquitin-conjugating enzyme E2 2; Belongs to the ubiquitin-conjugating enzyme family.	0.713

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Network Stats

number of nodes:

11

number of edges:

31

average node degree:

5.64

avg. local clustering coefficient:

0.952

expected number of edges:

20

PPI enrichment p-value:

0.0162

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1006

Beta-ketoacyl synthase, active site, and Condensation domain

3 of 5

2.38

1.7

0.00065

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005835

Fatty acid synthase complex

3 of 13

1.96

1.4

0.0018

GOCC:0005829

Cytosol

7 of 580

0.68

0.44

0.0213

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0596

Phosphopantetheine

2 of 7

2.06

0.74

0.0424

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00550

Phosphopantetheine attachment site

3 of 7

2.23

1.6

0.00092

PF14765

Polyketide synthase dehydratase

2 of 2

2.6

1.07

0.0113

PF00698

Acyl transferase domain

2 of 2

2.6

1.07

0.0113

PF00258

Flavodoxin

2 of 3

2.42

1.06

0.0113

PF02801

Beta-ketoacyl synthase, C-terminal domain

2 of 6

2.12

0.9

0.0209

(more ...)

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR036736

ACP-like superfamily

3 of 8

2.17

1.33

0.0031

IPR009081

Phosphopantetheine binding ACP domain

3 of 8

2.17

1.33

0.0031

IPR042104

Polyketide synthase, dehydratase domain superfamily

2 of 2

2.6

0.95

0.0186

IPR020807

Polyketide synthase, dehydratase domain

2 of 2

2.6

0.95

0.0186

IPR016035

Acyl transferase/acyl hydrolase/lysophospholipase

2 of 2

2.6

0.95

0.0186

(more ...)

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