AYL99_01740 protein (Fonsecaea erecta) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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gene co-occurrence

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Score

AYL99_01740

Cell division control protein 48; Belongs to the AAA ATPase family. (820 aa)

Predicted Functional Partners:

AYL99_06854

0.984

AYL99_00692

0.983

AYL99_01413

0.983

AYL99_08546

0.976

AYL99_02812

0.973

AYL99_03478

0.972

AYL99_01409

0.969

AYL99_08963

0.968

AYL99_04546

0.967

AYL99_10633

0.961

Your Current Organism:

Fonsecaea erecta

NCBI taxonomy Id: 1367422
Other names: F. erecta, Fonsecaea erecta V. A. Vicente, Najafzadeh, Sun & de Hoog 2013, Fonsecaea sp. RG-2013a

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AYL99_00692	AYL99_01409	A0A178ZXY9	A0A179A0B1	Uncharacterized protein.	OTU domain-containing protein.	0.964
AYL99_00692	AYL99_01740	A0A178ZXY9	A0A179A0Y6	Uncharacterized protein.	Cell division control protein 48; Belongs to the AAA ATPase family.	0.983
AYL99_00692	AYL99_03478	A0A178ZXY9	A0A178ZNB4	Uncharacterized protein.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.946
AYL99_00692	AYL99_04546	A0A178ZXY9	A0A178ZT20	Uncharacterized protein.	UBX domain-containing protein.	0.952
AYL99_00692	AYL99_06854	A0A178ZXY9	A0A178ZJI1	Uncharacterized protein.	MPN domain-containing protein.	0.888
AYL99_00692	AYL99_08546	A0A178ZXY9	A0A178ZDH1	Uncharacterized protein.	Uncharacterized protein.	0.945
AYL99_00692	AYL99_08963	A0A178ZXY9	A0A178ZBJ6	Uncharacterized protein.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.823
AYL99_01409	AYL99_00692	A0A179A0B1	A0A178ZXY9	OTU domain-containing protein.	Uncharacterized protein.	0.964
AYL99_01409	AYL99_01740	A0A179A0B1	A0A179A0Y6	OTU domain-containing protein.	Cell division control protein 48; Belongs to the AAA ATPase family.	0.969
AYL99_01409	AYL99_02812	A0A179A0B1	A0A178ZX66	OTU domain-containing protein.	RING-type domain-containing protein.	0.418
AYL99_01409	AYL99_06854	A0A179A0B1	A0A178ZJI1	OTU domain-containing protein.	MPN domain-containing protein.	0.962
AYL99_01409	AYL99_08546	A0A179A0B1	A0A178ZDH1	OTU domain-containing protein.	Uncharacterized protein.	0.968
AYL99_01413	AYL99_01740	A0A179A1H8	A0A179A0Y6	Response regulatory domain-containing protein.	Cell division control protein 48; Belongs to the AAA ATPase family.	0.983
AYL99_01740	AYL99_00692	A0A179A0Y6	A0A178ZXY9	Cell division control protein 48; Belongs to the AAA ATPase family.	Uncharacterized protein.	0.983
AYL99_01740	AYL99_01409	A0A179A0Y6	A0A179A0B1	Cell division control protein 48; Belongs to the AAA ATPase family.	OTU domain-containing protein.	0.969
AYL99_01740	AYL99_01413	A0A179A0Y6	A0A179A1H8	Cell division control protein 48; Belongs to the AAA ATPase family.	Response regulatory domain-containing protein.	0.983
AYL99_01740	AYL99_02812	A0A179A0Y6	A0A178ZX66	Cell division control protein 48; Belongs to the AAA ATPase family.	RING-type domain-containing protein.	0.973
AYL99_01740	AYL99_03478	A0A179A0Y6	A0A178ZNB4	Cell division control protein 48; Belongs to the AAA ATPase family.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.972
AYL99_01740	AYL99_04546	A0A179A0Y6	A0A178ZT20	Cell division control protein 48; Belongs to the AAA ATPase family.	UBX domain-containing protein.	0.967
AYL99_01740	AYL99_06854	A0A179A0Y6	A0A178ZJI1	Cell division control protein 48; Belongs to the AAA ATPase family.	MPN domain-containing protein.	0.984

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Network Stats

number of nodes:

11

number of edges:

21

average node degree:

3.82

avg. local clustering coefficient:

0.643

expected number of edges:

14

PPI enrichment p-value:

0.0389

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0019439

Aromatic compound catabolic process

8 of 56

1.57

2.65

7.00e-09

GO:0009056

Catabolic process

9 of 193

1.09

1.28

9.89e-07

GO:0042537

Benzene-containing compound metabolic process

3 of 10

1.89

1.25

0.0034

GO:0019619

3,4-dihydroxybenzoate catabolic process

2 of 3

2.24

0.82

0.0312

GO:0044282

Small molecule catabolic process

4 of 92

1.06

0.57

0.0371

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0051213

Dioxygenase activity

4 of 13

1.91

1.83

0.00016

GO:0005506

Iron ion binding

4 of 13

1.91

1.83

0.00016

GO:0008199

Ferric iron binding

2 of 3

2.24

0.97

0.0160

GO:0004497

Monooxygenase activity

3 of 20

1.59

0.95

0.0106

GO:0016702

Oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen

2 of 5

2.02

0.83

0.0278

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1699

Mixed, incl. Degradation of aromatic compounds, and Coenzyme A transferase

4 of 27

1.59

1.21

0.0022

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map01220

Degradation of aromatic compounds

5 of 30

1.64

2.02

1.07e-05

map00362

Benzoate degradation

5 of 31

1.62

2.0

1.07e-05

map00643

Styrene degradation

2 of 4

2.12

1.17

0.0061

map00361

Chlorocyclohexane and chlorobenzene degradation

2 of 5

2.02

1.13

0.0069

map00622

Xylene degradation

2 of 14

1.57

0.74

0.0321

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0223

Dioxygenase

3 of 8

1.99

1.47

0.0013

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00775

Dioxygenase

2 of 2

2.42

0.8

0.0349

PF00111

2Fe-2S iron-sulfur cluster binding domain

2 of 2

2.42

0.8

0.0349

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