STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFN52236.1Hydrogenase maturation protein, carbamoyl dehydratase HypE. (336 aa)    
Predicted Functional Partners:
SFN52263.1
Hydrogenase maturation protein HypD; Belongs to the HypD family.
 
 
 0.999
SFN52286.1
Hydrogenase maturation protein HypC.
 
 
 0.998
SFN52624.1
Hydrogenase maturation protein, carbamoyltransferase HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
 
 
 0.990
hypA
Hydrogenase-3 nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
  
 0.966
SFN52305.1
Hydrogenase nickel incorporation protein HypB.
 
  
 0.965
SFN52217.1
Formate hydrogenlyase transcriptional activator.
  
  
 0.790
SFN52463.1
NADH dehydrogenase subunit C.
 
 
 
 0.753
SFN35454.1
Flagellar motor switch protein FliG.
    
   0.723
SFN63533.1
Flagellar motor switch protein FliG; FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
    
   0.723
SFM96435.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
  
  
 0.640
Your Current Organism:
Izhakiella capsodis
NCBI taxonomy Id: 1367852
Other names: DSM 29293, Enterobacteriaceae bacterium N6PO6, Enterobacteriaceae bacterium N8PI1, Enterobacteriaceae bacterium N8PO1, I. capsodis, Izhakiella capsodis Aizenberg-Gershtein et al. 2016, LMG 28430, LMG:28430, strain N6PO6
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