Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
BV96_01210Molecular chaperone DnaJ. (205 aa)    
Predicted Functional Partners:
dnaK
Heat shock protein 70; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.959
BV96_01212
Cobalt chelatase.
 
     0.887
grpE_1
HSP-70 cofactor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependen [...]
  
 
 0.848
grpE_2
HSP-70 cofactor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependen [...]
  
 
 0.848
BV96_01211
Aerobic cobaltochelatase subunit CobS.
 
     0.830
groL
Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 0.806
groL-2
Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 0.806
atpF_1
F-type ATPase subunit b; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.
  
     0.766
atpF_2
F-type ATPase subunit b; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.
  
     0.766
BV96_01844
Putative uncharacterized protein precursor.
  
 
  0.760
Your Current Organism:
Sphingomonas paucimobilis
NCBI taxonomy Id: 13689
Other names: ATCC 10829 [[Flavobacterium devorans]], ATCC 29837, Bacillus devorans, CCUG 31192, CCUG 6518, CIP 100752, Chromobacterium devorans, DSM 30198 [[Flavobacterium devorans]], Flavobacterium devorans, GIFU 2395, GIFU:2395, IFO 13935, JCM 7516, LMG 4017 [[Flavobacterium devorans]], LMG:4017 [[Flavobacterium devorans]], NBRC 13935, NCAIM B.01654, NCPPB 3838, NCTC 11030, NRRL B-54 [[Flavobacterium devorans]], Pseudomonas paucimobilis, S. paucimobilis
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