| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BV96_01918 | BV96_04070 | BV96_01918 | BV96_04070 | Phosphoserine phosphatase. | tRNA synthetase class II. | 0.650 |
| BV96_01918 | BV96_04072 | BV96_01918 | BV96_04072 | Phosphoserine phosphatase. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | 0.770 |
| BV96_01918 | glyA | BV96_01918 | BV96_01893 | Phosphoserine phosphatase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.654 |
| BV96_01918 | hisA | BV96_01918 | BV96_03389 | Phosphoserine phosphatase. | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | 0.694 |
| BV96_01918 | hisB | BV96_01918 | BV96_03391 | Phosphoserine phosphatase. | Imidazoleglycerol-phosphate dehydratase. | 0.691 |
| BV96_01918 | hisD | BV96_01918 | BV96_01139 | Phosphoserine phosphatase. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.677 |
| BV96_01918 | hisF | BV96_01918 | BV96_03388 | Phosphoserine phosphatase. | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.779 |
| BV96_01918 | hisH | BV96_01918 | BV96_03390 | Phosphoserine phosphatase. | Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.712 |
| BV96_01918 | hisI | BV96_01918 | BV96_01879 | Phosphoserine phosphatase. | Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.694 |
| BV96_01918 | miaA | BV96_01918 | BV96_01919 | Phosphoserine phosphatase. | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.758 |
| BV96_04070 | BV96_01918 | BV96_04070 | BV96_01918 | tRNA synthetase class II. | Phosphoserine phosphatase. | 0.650 |
| BV96_04070 | BV96_04072 | BV96_04070 | BV96_04072 | tRNA synthetase class II. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | 0.605 |
| BV96_04070 | hisA | BV96_04070 | BV96_03389 | tRNA synthetase class II. | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | 0.935 |
| BV96_04070 | hisB | BV96_04070 | BV96_03391 | tRNA synthetase class II. | Imidazoleglycerol-phosphate dehydratase. | 0.929 |
| BV96_04070 | hisD | BV96_04070 | BV96_01139 | tRNA synthetase class II. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.920 |
| BV96_04070 | hisF | BV96_04070 | BV96_03388 | tRNA synthetase class II. | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.938 |
| BV96_04070 | hisH | BV96_04070 | BV96_03390 | tRNA synthetase class II. | Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.923 |
| BV96_04070 | hisI | BV96_04070 | BV96_01879 | tRNA synthetase class II. | Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.912 |
| BV96_04072 | BV96_01918 | BV96_04072 | BV96_01918 | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | Phosphoserine phosphatase. | 0.770 |
| BV96_04072 | BV96_04070 | BV96_04072 | BV96_04070 | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | tRNA synthetase class II. | 0.605 |