Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pdhAPyruvate dehydrogenase (Acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (315 aa)    
Predicted Functional Partners:
BV96_01933
Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 0.999
BV96_03134
2-oxoisovalerate dehydrogenase subunit beta.
 0.999
BV96_02975
Dihydrolipoamide acetyltransferase, long form; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.965
BV96_03367
Branched-chain alpha-keto acid dehydrogenase subunit E2; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.965
BV96_03133
Branched-chain alpha-keto acid dehydrogenase subunit E2.
 
 0.940
BV96_01537
Dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 
 0.938
pdhD
Dihydrolipoyl dehydrogenase.
 
 
 0.867
BV96_01538
Dihydrolipoyl dehydrogenase.
 
 
 0.770
BV96_04345
Mercuric reductase.
 
 
 0.715
BV96_01721
Glutathione reductase; Maintains high levels of reduced glutathione.
 
 
 0.691
Your Current Organism:
Sphingomonas paucimobilis
NCBI taxonomy Id: 13689
Other names: ATCC 10829 [[Flavobacterium devorans]], ATCC 29837, Bacillus devorans, CCUG 31192, CCUG 6518, CIP 100752, Chromobacterium devorans, DSM 30198 [[Flavobacterium devorans]], Flavobacterium devorans, GIFU 2395, GIFU:2395, IFO 13935, JCM 7516, LMG 4017 [[Flavobacterium devorans]], LMG:4017 [[Flavobacterium devorans]], NBRC 13935, NCAIM B.01654, NCPPB 3838, NCTC 11030, NRRL B-54 [[Flavobacterium devorans]], Pseudomonas paucimobilis, S. paucimobilis
Server load: medium (48%) [HD]