STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobB_1NAD-dependent deacylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sirtuin family. Class III subfamily. (232 aa)    
Predicted Functional Partners:
OAH42923.1
AsnC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.992
nadE
NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
   
 0.953
nadD
Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
   
 0.922
ppnK
NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
 
 0.918
OAH35254.1
NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.910
OAH42308.1
NADH pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Nudix hydrolase family.
    
 0.907
OAH35253.1
Pyridine nucleotide transhydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.905
OAH46055.1
Nucleoside hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.905
OAH42842.1
Twin-arginine translocation pathway signal protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.905
OAH35252.1
NAD synthetase; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
    
  0.900
Your Current Organism:
Sphingobium yanoikuyae
NCBI taxonomy Id: 13690
Other names: ATCC 51230, Beijerinckia sp. B1, CCUG 28380, CCUG 31205, CIP 106726, DSM 7462, GIFU 9882, GIFU:9882, IFO 15102, JCM 7371, LMG 11252, LMG:11252, NBRC 15102, S. yanoikuyae, Sphingobium sp. TJ, Sphingomonas yanoikuyae
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