Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
clpPATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. (211 aa)    
Predicted Functional Partners:
clpX
ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
 0.999
clpA
ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family.
 
 
 0.859
clpB
ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
 
 
 0.858
OAH37872.1
ATP-dependent chaperone ClpB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.858
clpS
ATP-dependent Clp protease adaptor ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.
   
 
 0.821
tig
Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.
 
  
 0.801
rplK
50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
  
  
 0.795
OAH45898.1
Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   0.794
OAH42914.1
Diacylglycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.782
lon_2
DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.782
Your Current Organism:
Sphingobium yanoikuyae
NCBI taxonomy Id: 13690
Other names: ATCC 51230, Beijerinckia sp. B1, CCUG 28380, CCUG 31205, CIP 106726, DSM 7462, GIFU 9882, GIFU:9882, IFO 15102, JCM 7371, LMG 11252, LMG:11252, NBRC 15102, S. yanoikuyae, Sphingobium sp. TJ, Sphingomonas yanoikuyae
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