| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| OAH40962.1 | OAH42611.1 | AX777_21120 | AX777_05010 | acetate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | methylmalonyl-CoA mutase; MDM; functions in conversion of succinate to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.614 |
| OAH40962.1 | OAH42731.1 | AX777_21120 | AX777_05690 | acetate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | acetyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.925 |
| OAH40962.1 | OAH45865.1 | AX777_21120 | AX777_04320 | acetate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Branched-chain alpha-keto acid dehydrogenase subunit E2; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.906 |
| OAH40962.1 | accC | AX777_21120 | AX777_06500 | acetate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.921 |
| OAH40962.1 | acsA_1 | AX777_21120 | AX777_07680 | acetate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.924 |
| OAH40962.1 | acsA_2 | AX777_21120 | AX777_00945 | acetate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | TonB-dependent receptor; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.924 |
| OAH40962.1 | glcB | AX777_21120 | AX777_14890 | acetate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.934 |
| OAH40962.1 | sucC | AX777_21120 | AX777_22820 | acetate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | succinate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.836 |
| OAH40962.1 | sucD | AX777_21120 | AX777_11335 | acetate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | succinate--CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.824 |
| OAH42611.1 | OAH40962.1 | AX777_05010 | AX777_21120 | methylmalonyl-CoA mutase; MDM; functions in conversion of succinate to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. | acetate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.614 |
| OAH42611.1 | OAH42731.1 | AX777_05010 | AX777_05690 | methylmalonyl-CoA mutase; MDM; functions in conversion of succinate to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. | acetyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.950 |
| OAH42611.1 | OAH45865.1 | AX777_05010 | AX777_04320 | methylmalonyl-CoA mutase; MDM; functions in conversion of succinate to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Branched-chain alpha-keto acid dehydrogenase subunit E2; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.820 |
| OAH42611.1 | acsA_1 | AX777_05010 | AX777_07680 | methylmalonyl-CoA mutase; MDM; functions in conversion of succinate to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.614 |
| OAH42611.1 | acsA_2 | AX777_05010 | AX777_00945 | methylmalonyl-CoA mutase; MDM; functions in conversion of succinate to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. | TonB-dependent receptor; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.614 |
| OAH42611.1 | sdhB | AX777_05010 | AX777_11315 | methylmalonyl-CoA mutase; MDM; functions in conversion of succinate to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Succinate dehydrogenase iron-sulfur subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.529 |
| OAH42611.1 | sucC | AX777_05010 | AX777_22820 | methylmalonyl-CoA mutase; MDM; functions in conversion of succinate to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. | succinate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.955 |
| OAH42611.1 | sucD | AX777_05010 | AX777_11335 | methylmalonyl-CoA mutase; MDM; functions in conversion of succinate to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. | succinate--CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.966 |
| OAH42731.1 | OAH40962.1 | AX777_05690 | AX777_21120 | acetyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | acetate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.925 |
| OAH42731.1 | OAH42611.1 | AX777_05690 | AX777_05010 | acetyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | methylmalonyl-CoA mutase; MDM; functions in conversion of succinate to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.950 |
| OAH42731.1 | OAH45865.1 | AX777_05690 | AX777_04320 | acetyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Branched-chain alpha-keto acid dehydrogenase subunit E2; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.911 |