STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hmgAHomogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. (438 aa)    
Predicted Functional Partners:
hppD
4-hydroxyphenylpyruvate dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
OAH46473.1
3-keto-5-aminohexanoate cleavage protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.991
FahA
Fumarylacetoacetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.978
MaiA
Maleylacetoacetate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.975
OAH46956.1
Phenylalanine-4-hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.952
OAH44672.1
Fumarylacetoacetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.910
OAH46961.1
2Fe-2S ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.843
OAH46957.1
Aromatic amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.832
OAH44727.1
Maleylacetoacetate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.788
OAH45889.1
Fumarylacetoacetate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.555
Your Current Organism:
Sphingobium yanoikuyae
NCBI taxonomy Id: 13690
Other names: ATCC 51230, Beijerinckia sp. B1, CCUG 28380, CCUG 31205, CIP 106726, DSM 7462, GIFU 9882, GIFU:9882, IFO 15102, JCM 7371, LMG 11252, LMG:11252, NBRC 15102, S. yanoikuyae, Sphingobium sp. TJ, Sphingomonas yanoikuyae
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