| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| OAH39569.1 | OAH46047.1 | AX777_24855 | AX777_09730 | ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.883 |
| OAH39569.1 | OAH46127.1 | AX777_24855 | AX777_10180 | ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA topoisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.786 |
| OAH40831.1 | OAH46127.1 | AX777_19140 | AX777_10180 | Histone deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA topoisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.740 |
| OAH41328.1 | OAH46127.1 | AX777_11635 | AX777_10180 | Peptide chain release factor I; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA topoisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.719 |
| OAH46047.1 | OAH39569.1 | AX777_09730 | AX777_24855 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.883 |
| OAH46047.1 | OAH46127.1 | AX777_09730 | AX777_10180 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA topoisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.774 |
| OAH46047.1 | OAH46720.1 | AX777_09730 | AX777_17160 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.883 |
| OAH46047.1 | RecQ | AX777_09730 | AX777_08465 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.867 |
| OAH46047.1 | gyrB | AX777_09730 | AX777_15520 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.908 |
| OAH46047.1 | parE | AX777_09730 | AX777_05640 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. | 0.783 |
| OAH46047.1 | rnhB | AX777_09730 | AX777_10615 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.913 |
| OAH46127.1 | OAH39569.1 | AX777_10180 | AX777_24855 | DNA topoisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.786 |
| OAH46127.1 | OAH40831.1 | AX777_10180 | AX777_19140 | DNA topoisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Histone deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.740 |
| OAH46127.1 | OAH41328.1 | AX777_10180 | AX777_11635 | DNA topoisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptide chain release factor I; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.719 |
| OAH46127.1 | OAH46047.1 | AX777_10180 | AX777_09730 | DNA topoisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.774 |
| OAH46127.1 | OAH46720.1 | AX777_10180 | AX777_17160 | DNA topoisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.787 |
| OAH46127.1 | RecQ | AX777_10180 | AX777_08465 | DNA topoisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.836 |
| OAH46127.1 | gyrB | AX777_10180 | AX777_15520 | DNA topoisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.791 |
| OAH46127.1 | parE | AX777_10180 | AX777_05640 | DNA topoisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. | 0.791 |
| OAH46127.1 | prfB | AX777_10180 | AX777_10310 | DNA topoisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | 0.719 |
