node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
OAH42381.1 | OAH43151.1 | AX777_14065 | AX777_15895 | Peptidase S14; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone Hsp70; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.534 |
OAH42381.1 | OAH46563.1 | AX777_14065 | AX777_01495 | Peptidase S14; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone HscC; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.534 |
OAH42381.1 | dnaK | AX777_14065 | AX777_20135 | Peptidase S14; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.534 |
OAH42381.1 | dnaK-2 | AX777_14065 | AX777_23120 | Peptidase S14; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone DnaK; Heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.534 |
OAH42381.1 | grpE | AX777_14065 | AX777_10420 | Peptidase S14; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.636 |
OAH42381.1 | hrcA | AX777_14065 | AX777_10415 | Peptidase S14; Derived by automated computational analysis using gene prediction method: Protein Homology. | Heat-inducible transcriptional repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.764 |
OAH43149.1 | OAH43151.1 | AX777_15885 | AX777_15895 | Molecular chaperone DnaJ; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone Hsp70; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.722 |
OAH43149.1 | OAH46563.1 | AX777_15885 | AX777_01495 | Molecular chaperone DnaJ; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone HscC; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.728 |
OAH43149.1 | dnaK | AX777_15885 | AX777_20135 | Molecular chaperone DnaJ; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.728 |
OAH43149.1 | dnaK-2 | AX777_15885 | AX777_23120 | Molecular chaperone DnaJ; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone DnaK; Heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.728 |
OAH43149.1 | grpE | AX777_15885 | AX777_10420 | Molecular chaperone DnaJ; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.794 |
OAH43149.1 | hrcA | AX777_15885 | AX777_10415 | Molecular chaperone DnaJ; Derived by automated computational analysis using gene prediction method: Protein Homology. | Heat-inducible transcriptional repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.670 |
OAH43151.1 | OAH42381.1 | AX777_15895 | AX777_14065 | Molecular chaperone Hsp70; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptidase S14; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.534 |
OAH43151.1 | OAH43149.1 | AX777_15895 | AX777_15885 | Molecular chaperone Hsp70; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone DnaJ; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.722 |
OAH43151.1 | OAH45192.1 | AX777_15895 | AX777_06665 | Molecular chaperone Hsp70; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone DnaJ; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.722 |
OAH43151.1 | clpP | AX777_15895 | AX777_04525 | Molecular chaperone Hsp70; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.537 |
OAH43151.1 | dnaJ | AX777_15895 | AX777_20130 | Molecular chaperone Hsp70; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.797 |
OAH43151.1 | grpE | AX777_15895 | AX777_10420 | Molecular chaperone Hsp70; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.952 |
OAH43151.1 | hrcA | AX777_15895 | AX777_10415 | Molecular chaperone Hsp70; Derived by automated computational analysis using gene prediction method: Protein Homology. | Heat-inducible transcriptional repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.883 |
OAH45192.1 | OAH43151.1 | AX777_06665 | AX777_15895 | Molecular chaperone DnaJ; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone Hsp70; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.722 |