| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| OAH42381.1 | OAH43151.1 | AX777_14065 | AX777_15895 | Peptidase S14; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone Hsp70; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.409 |
| OAH42381.1 | OAH46563.1 | AX777_14065 | AX777_01495 | Peptidase S14; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone HscC; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.409 |
| OAH42381.1 | clpA | AX777_14065 | AX777_12430 | Peptidase S14; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family. | 0.822 |
| OAH42381.1 | clpS | AX777_14065 | AX777_10075 | Peptidase S14; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent Clp protease adaptor ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | 0.437 |
| OAH42381.1 | dnaK | AX777_14065 | AX777_20135 | Peptidase S14; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.409 |
| OAH42381.1 | dnaK-2 | AX777_14065 | AX777_23120 | Peptidase S14; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone DnaK; Heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.409 |
| OAH42381.1 | grpE | AX777_14065 | AX777_10420 | Peptidase S14; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.514 |
| OAH43151.1 | OAH42381.1 | AX777_15895 | AX777_14065 | Molecular chaperone Hsp70; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptidase S14; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.409 |
| OAH43151.1 | clpA | AX777_15895 | AX777_12430 | Molecular chaperone Hsp70; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family. | 0.732 |
| OAH43151.1 | clpP | AX777_15895 | AX777_04525 | Molecular chaperone Hsp70; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.409 |
| OAH43151.1 | dnaJ | AX777_15895 | AX777_20130 | Molecular chaperone Hsp70; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.869 |
| OAH43151.1 | grpE | AX777_15895 | AX777_10420 | Molecular chaperone Hsp70; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.968 |
| OAH43151.1 | htpG | AX777_15895 | AX777_25515 | Molecular chaperone Hsp70; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone HtpG; Molecular chaperone. Has ATPase activity. | 0.948 |
| OAH46563.1 | OAH42381.1 | AX777_01495 | AX777_14065 | Molecular chaperone HscC; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptidase S14; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.409 |
| OAH46563.1 | clpA | AX777_01495 | AX777_12430 | Molecular chaperone HscC; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family. | 0.728 |
| OAH46563.1 | clpP | AX777_01495 | AX777_04525 | Molecular chaperone HscC; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.625 |
| OAH46563.1 | dnaJ | AX777_01495 | AX777_20130 | Molecular chaperone HscC; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.990 |
| OAH46563.1 | grpE | AX777_01495 | AX777_10420 | Molecular chaperone HscC; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.978 |
| OAH46563.1 | htpG | AX777_01495 | AX777_25515 | Molecular chaperone HscC; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone HtpG; Molecular chaperone. Has ATPase activity. | 0.960 |
| clpA | OAH42381.1 | AX777_12430 | AX777_14065 | ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family. | Peptidase S14; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.822 |
