node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
A0A1X2H0S3 | A0A1X2H3D7 | A0A1X2H0S3 | A0A1X2H3D7 | Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. | Elongator complex protein 4. | 0.994 |
A0A1X2H0S3 | A0A1X2H738 | A0A1X2H0S3 | A0A1X2H738 | Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. | NUC153 domain-containing protein. | 0.853 |
A0A1X2H0S3 | A0A1X2HAK1 | A0A1X2H0S3 | A0A1X2HAK1 | Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. | Chromatin associated protein KTI12. | 0.881 |
A0A1X2H0S3 | A0A1X2HAM1 | A0A1X2H0S3 | A0A1X2HAM1 | Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. | Diphthamide biosynthesis protein Dph3. | 0.844 |
A0A1X2H0S3 | A0A1X2HB32 | A0A1X2H0S3 | A0A1X2HB32 | Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. | WD40-repeat-containing domain protein. | 0.979 |
A0A1X2H0S3 | A0A1X2HBK4 | A0A1X2H0S3 | A0A1X2HBK4 | Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. | Uncharacterized protein. | 0.766 |
A0A1X2H0S3 | A0A1X2HNH6 | A0A1X2H0S3 | A0A1X2HNH6 | Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. | Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. | 0.996 |
A0A1X2H0S3 | A0A1X2HQC3 | A0A1X2H0S3 | A0A1X2HQC3 | Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. | Elongator complex protein 5. | 0.982 |
A0A1X2H0S3 | A0A1X2HQK7 | A0A1X2H0S3 | A0A1X2HQK7 | Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. | DPBB_1 domain-containing protein. | 0.941 |
A0A1X2H0S3 | UBA4 | A0A1X2H0S3 | A0A1X2H117 | Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. | Adenylyltransferase and sulfurtransferase UBA4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Acts by mediating the C-terminal thiocarboxylation of sulfur carrier URM1. Its N-terminus first activates URM1 as acyl-adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1. Subseque [...] | 0.740 |
A0A1X2H3D7 | A0A1X2H0S3 | A0A1X2H3D7 | A0A1X2H0S3 | Elongator complex protein 4. | Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. | 0.994 |
A0A1X2H3D7 | A0A1X2HAK1 | A0A1X2H3D7 | A0A1X2HAK1 | Elongator complex protein 4. | Chromatin associated protein KTI12. | 0.699 |
A0A1X2H3D7 | A0A1X2HAM1 | A0A1X2H3D7 | A0A1X2HAM1 | Elongator complex protein 4. | Diphthamide biosynthesis protein Dph3. | 0.523 |
A0A1X2H3D7 | A0A1X2HB32 | A0A1X2H3D7 | A0A1X2HB32 | Elongator complex protein 4. | WD40-repeat-containing domain protein. | 0.938 |
A0A1X2H3D7 | A0A1X2HBK4 | A0A1X2H3D7 | A0A1X2HBK4 | Elongator complex protein 4. | Uncharacterized protein. | 0.971 |
A0A1X2H3D7 | A0A1X2HNH6 | A0A1X2H3D7 | A0A1X2HNH6 | Elongator complex protein 4. | Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. | 0.989 |
A0A1X2H3D7 | A0A1X2HQC3 | A0A1X2H3D7 | A0A1X2HQC3 | Elongator complex protein 4. | Elongator complex protein 5. | 0.997 |
A0A1X2H3D7 | A0A1X2HQK7 | A0A1X2H3D7 | A0A1X2HQK7 | Elongator complex protein 4. | DPBB_1 domain-containing protein. | 0.970 |
A0A1X2H3D7 | UBA4 | A0A1X2H3D7 | A0A1X2H117 | Elongator complex protein 4. | Adenylyltransferase and sulfurtransferase UBA4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Acts by mediating the C-terminal thiocarboxylation of sulfur carrier URM1. Its N-terminus first activates URM1 as acyl-adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1. Subseque [...] | 0.742 |
A0A1X2H738 | A0A1X2H0S3 | A0A1X2H738 | A0A1X2H0S3 | NUC153 domain-containing protein. | Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. | 0.853 |