STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1X2H0S3Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. (1287 aa)    
Predicted Functional Partners:
A0A1X2HNH6
Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.
   
 0.996
A0A1X2H3D7
Elongator complex protein 4.
   
 0.994
A0A1X2HQC3
Elongator complex protein 5.
   
 0.982
A0A1X2HB32
WD40-repeat-containing domain protein.
   
 0.979
A0A1X2HQK7
DPBB_1 domain-containing protein.
   
 0.941
A0A1X2HAK1
Chromatin associated protein KTI12.
    
 
 0.881
A0A1X2H738
NUC153 domain-containing protein.
   
    0.853
A0A1X2HAM1
Diphthamide biosynthesis protein Dph3.
   
 
 0.844
A0A1X2HBK4
Uncharacterized protein.
    
 0.766
UBA4
Adenylyltransferase and sulfurtransferase UBA4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Acts by mediating the C-terminal thiocarboxylation of sulfur carrier URM1. Its N-terminus first activates URM1 as acyl-adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1. Subseque [...]
   
 
 0.740
Your Current Organism:
Syncephalastrum racemosum
NCBI taxonomy Id: 13706
Other names: S. racemosum, fungal sp. RS07OS
Server load: low (20%) [HD]