STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1X2HTM8TPR_REGION domain-containing protein. (935 aa)    
Predicted Functional Partners:
A0A1X2GZL4
RNA pol II accessory factor, Cdc73 family-domain-containing protein.
   
 0.999
A0A1X2HMX7
Uncharacterized protein.
   
 0.999
A0A1X2HUX9
Leo1-like protein-domain-containing protein.
   
 0.999
A0A1X2H0T6
WD40-repeat-containing domain protein.
    
 0.998
A0A1X2H0X4
FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]
   
 0.997
A0A1X2HID5
Plus3 domain-containing protein.
   
 0.997
A0A1X2HB90
FACT complex subunit-domain-containing protein.
   
 0.989
A0A1X2HL65
Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.
    
 0.980
A0A1X2H758
RNA polymerase Rpb3/Rpb11 dimerization domain-containing protein.
   
 0.976
A0A1X2HB15
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.975
Your Current Organism:
Syncephalastrum racemosum
NCBI taxonomy Id: 13706
Other names: S. racemosum, fungal sp. RS07OS
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.