chiPu_0005132 protein (Chiloscyllium punctatum)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

chiPu_0005132

Uncharacterized protein. (1026 aa)

Predicted Functional Partners:

chiPu_0022000

0.993

chiPu_0017755

0.988

chiPu_0014364

0.988

chiPu_0029254

0.974

chiPu_0013517

0.956

chiPu_0014704

0.941

chiPu_0005289

0.939

chiPu_0005290

0.939

chiPu_0002510

0.913

chiPu_0005134

0.902

Your Current Organism:

Chiloscyllium punctatum

NCBI taxonomy Id: 137246
Other names: C. punctatum, brownbanded bambooshark

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
chiPu_0002510	chiPu_0005132	A0A401S186	A0A401S8I9	Uncharacterized protein.	Uncharacterized protein.	0.913
chiPu_0002510	chiPu_0014364	A0A401S186	A0A401SZS7	Uncharacterized protein.	Uncharacterized protein.	0.775
chiPu_0002510	chiPu_0017755	A0A401S186	A0A401RIN0	Uncharacterized protein.	Uncharacterized protein.	0.775
chiPu_0002510	chiPu_0022000	A0A401S186	A0A401RH67	Uncharacterized protein.	Fibronectin type-III domain-containing protein.	0.804
chiPu_0005132	chiPu_0002510	A0A401S8I9	A0A401S186	Uncharacterized protein.	Uncharacterized protein.	0.913
chiPu_0005132	chiPu_0005134	A0A401S8I9	A0A401S8M0	Uncharacterized protein.	Uncharacterized protein.	0.902
chiPu_0005132	chiPu_0005289	A0A401S8I9	A0A401S8Y2	Uncharacterized protein.	Uncharacterized protein.	0.939
chiPu_0005132	chiPu_0005290	A0A401S8I9	A0A401S954	Uncharacterized protein.	Uncharacterized protein.	0.939
chiPu_0005132	chiPu_0013517	A0A401S8I9	A0A401SXA1	Uncharacterized protein.	Uncharacterized protein.	0.956
chiPu_0005132	chiPu_0014364	A0A401S8I9	A0A401SZS7	Uncharacterized protein.	Uncharacterized protein.	0.988
chiPu_0005132	chiPu_0014704	A0A401S8I9	A0A401T0M5	Uncharacterized protein.	Uncharacterized protein.	0.941
chiPu_0005132	chiPu_0017755	A0A401S8I9	A0A401RIN0	Uncharacterized protein.	Uncharacterized protein.	0.988
chiPu_0005132	chiPu_0022000	A0A401S8I9	A0A401RH67	Uncharacterized protein.	Fibronectin type-III domain-containing protein.	0.993
chiPu_0005132	chiPu_0029254	A0A401S8I9	A0A401TS10	Uncharacterized protein.	Uncharacterized protein.	0.974
chiPu_0005134	chiPu_0005132	A0A401S8M0	A0A401S8I9	Uncharacterized protein.	Uncharacterized protein.	0.902
chiPu_0005134	chiPu_0014704	A0A401S8M0	A0A401T0M5	Uncharacterized protein.	Uncharacterized protein.	0.496
chiPu_0005289	chiPu_0005132	A0A401S8Y2	A0A401S8I9	Uncharacterized protein.	Uncharacterized protein.	0.939
chiPu_0005289	chiPu_0014364	A0A401S8Y2	A0A401SZS7	Uncharacterized protein.	Uncharacterized protein.	0.927
chiPu_0005289	chiPu_0014704	A0A401S8Y2	A0A401T0M5	Uncharacterized protein.	Uncharacterized protein.	0.905
chiPu_0005289	chiPu_0017755	A0A401S8Y2	A0A401RIN0	Uncharacterized protein.	Uncharacterized protein.	0.927

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

22

average node degree:

4

avg. local clustering coefficient:

0.794

expected number of edges:

13

PPI enrichment p-value:

0.0158

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0022900

Electron transport chain

6 of 86

1.45

1.61

4.69e-05

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004556

Alpha-amylase activity

2 of 2

2.61

0.83

0.0314

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:31379757

(2019) Hydrostatic Pressure Helps to Cultivate an Original Anaerobic Bacterium From the Atlantis Massif Subseafloor (IODP Expedition 357): Petrocella atlantisensis gen. nov. sp. nov.

3 of 3

2.61

1.97

0.00023

PMID:36303868

(2022) White common bean extract remodels the gut microbiota and ameliorates type 2 diabetes and its complications: A randomized double-blinded placebo-controlled trial.

2 of 2

2.61

0.97

0.0176

PMID:30100182

(2018) Cooperative Metabolic Adaptations in the Host Can Favor Asymptomatic Infection and Select for Attenuated Virulence in an Enteric Pathogen.

2 of 3

2.43

0.94

0.0195

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3649

This conserved region includes the FMN-binding site of the NqrC protein as well as the NosR and NirI regulatory proteins., and Electron transport

6 of 10

2.39

4.69

3.40e-10

CL:3652

Mixed, incl. RnfC Barrel sandwich hybrid domain, and This conserved region includes the FMN-binding site of the NqrC protein as well as the NosR and NirI regulatory proteins.

5 of 5

2.61

4.39

4.00e-09

CL:5617

Alpha-amylase domain, and Glycosyl hydrolases family 31

2 of 5

2.21

0.83

0.0296

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0249

Electron transport

6 of 31

1.9

3.23

2.43e-08

KW-1278

Translocase

5 of 43

1.67

2.13

6.56e-06

KW-0106

Calcium

2 of 8

2.01

1.0

0.0127

KW-0997

Cell inner membrane

5 of 162

1.1

0.87

0.0023

KW-0004

4Fe-4S

3 of 58

1.32

0.78

0.0160

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00642

Alpha-amylase domain

2 of 4

2.31

1.04

0.0118

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