chiPu_0006941 protein (Chiloscyllium punctatum)

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second shell of interactors

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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Gene Fusion

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Score

chiPu_0006941

N-acetyltransferase domain-containing protein. (199 aa)

Predicted Functional Partners:

chiPu_0009229

0.998

chiPu_0031411

0.997

chiPu_0012299

0.970

chiPu_0002300

0.952

chiPu_0008600

0.924

chiPu_0015080

0.906

chiPu_0002042

0.877

chiPu_0007713

0.868

chiPu_0009451

0.868

chiPu_0013174

0.857

Your Current Organism:

Chiloscyllium punctatum

NCBI taxonomy Id: 137246
Other names: C. punctatum, brownbanded bambooshark

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
chiPu_0002042	chiPu_0006941	A0A401RZQ9	A0A401SDP2	Ribosomal_L23eN domain-containing protein; Belongs to the universal ribosomal protein uL23 family.	N-acetyltransferase domain-containing protein.	0.877
chiPu_0002042	chiPu_0009229	A0A401RZQ9	A0A401SK66	Ribosomal_L23eN domain-containing protein; Belongs to the universal ribosomal protein uL23 family.	Uncharacterized protein.	0.871
chiPu_0002042	chiPu_0015080	A0A401RZQ9	A0A401T1R7	Ribosomal_L23eN domain-containing protein; Belongs to the universal ribosomal protein uL23 family.	Uncharacterized protein.	0.869
chiPu_0002042	chiPu_0031411	A0A401RZQ9	A0A401TW97	Ribosomal_L23eN domain-containing protein; Belongs to the universal ribosomal protein uL23 family.	Uncharacterized protein.	0.905
chiPu_0002300	chiPu_0006941	A0A401S0H6	A0A401SDP2	RRN7-type domain-containing protein.	N-acetyltransferase domain-containing protein.	0.952
chiPu_0002300	chiPu_0007713	A0A401S0H6	A0A401SFX7	RRN7-type domain-containing protein.	CBFD_NFYB_HMF domain-containing protein.	0.928
chiPu_0002300	chiPu_0008600	A0A401S0H6	A0A401SII0	RRN7-type domain-containing protein.	Uncharacterized protein.	0.999
chiPu_0002300	chiPu_0009451	A0A401S0H6	A0A401SKT4	RRN7-type domain-containing protein.	CBFD_NFYB_HMF domain-containing protein.	0.928
chiPu_0006941	chiPu_0002042	A0A401SDP2	A0A401RZQ9	N-acetyltransferase domain-containing protein.	Ribosomal_L23eN domain-containing protein; Belongs to the universal ribosomal protein uL23 family.	0.877
chiPu_0006941	chiPu_0002300	A0A401SDP2	A0A401S0H6	N-acetyltransferase domain-containing protein.	RRN7-type domain-containing protein.	0.952
chiPu_0006941	chiPu_0007713	A0A401SDP2	A0A401SFX7	N-acetyltransferase domain-containing protein.	CBFD_NFYB_HMF domain-containing protein.	0.868
chiPu_0006941	chiPu_0008600	A0A401SDP2	A0A401SII0	N-acetyltransferase domain-containing protein.	Uncharacterized protein.	0.924
chiPu_0006941	chiPu_0009229	A0A401SDP2	A0A401SK66	N-acetyltransferase domain-containing protein.	Uncharacterized protein.	0.998
chiPu_0006941	chiPu_0009451	A0A401SDP2	A0A401SKT4	N-acetyltransferase domain-containing protein.	CBFD_NFYB_HMF domain-containing protein.	0.868
chiPu_0006941	chiPu_0012299	A0A401SDP2	A0A401STY3	N-acetyltransferase domain-containing protein.	Uncharacterized protein.	0.970
chiPu_0006941	chiPu_0013174	A0A401SDP2	A0A401SWB8	N-acetyltransferase domain-containing protein.	Uncharacterized protein.	0.857
chiPu_0006941	chiPu_0015080	A0A401SDP2	A0A401T1R7	N-acetyltransferase domain-containing protein.	Uncharacterized protein.	0.906
chiPu_0006941	chiPu_0031411	A0A401SDP2	A0A401TW97	N-acetyltransferase domain-containing protein.	Uncharacterized protein.	0.997
chiPu_0007713	chiPu_0002300	A0A401SFX7	A0A401S0H6	CBFD_NFYB_HMF domain-containing protein.	RRN7-type domain-containing protein.	0.928
chiPu_0007713	chiPu_0006941	A0A401SFX7	A0A401SDP2	CBFD_NFYB_HMF domain-containing protein.	N-acetyltransferase domain-containing protein.	0.868

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

54

average node degree:

9.82

avg. local clustering coefficient:

0.982

expected number of edges:

12

PPI enrichment p-value:

< 1.0e-16

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006383

Transcription by RNA polymerase III

6 of 20

2.48

4.96

1.46e-10

GO:0006384

Transcription initiation from RNA polymerase III promoter

4 of 6

2.83

3.83

7.83e-08

GO:0006351

Transcription, DNA-templated

8 of 185

1.64

2.93

2.04e-09

GO:0006352

DNA-templated transcription, initiation

5 of 54

1.97

2.8

8.23e-07

GO:0070898

RNA polymerase III preinitiation complex assembly

2 of 2

3.0

1.61

0.0012

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0140223

General transcription initiation factor activity

3 of 16

2.28

1.61

0.00092

GO:0050464

Nitrate reductase (NADPH) activity

2 of 2

3.0

1.41

0.0028

GO:0000995

RNA polymerase III general transcription initiation factor activity

2 of 2

3.0

1.41

0.0028

GO:0043546

Molybdopterin cofactor binding

2 of 5

2.61

1.31

0.0041

GO:0030151

Molybdenum ion binding

2 of 11

2.26

1.14

0.0077

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0090576

RNA polymerase III transcription regulator complex

5 of 5

3.0

5.49

6.98e-11

GO:0000127

Transcription factor TFIIIC complex

3 of 3

3.0

2.96

4.07e-06

GO:0000126

Transcription factor TFIIIB complex

2 of 2

3.0

1.64

0.0011

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:834

Transcription factor TFIIIC complex, and Histidine phosphatase superfamily, clade-1

4 of 5

2.91

3.77

1.14e-07

CL:1661

RNA polymerase III complex, and Transcription factor TFIIIB complex

3 of 20

2.18

1.84

0.00028

CL:13449

Oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor, and Cytochrome b5, heme-binding site

2 of 7

2.46

1.42

0.0024

CL:1481

RNA Polymerase II Pre-transcription Events, and RNA polymerase

4 of 117

1.54

1.41

0.00049

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-76066

RNA Polymerase III Transcription Initiation From Type 2 Promoter

7 of 24

2.47

6.21

1.98e-13

MAP-76061

RNA Polymerase III Transcription Initiation From Type 1 Promoter

7 of 24

2.47

6.21

1.98e-13

MAP-76046

RNA Polymerase III Transcription Initiation

7 of 24

2.47

6.21

1.98e-13

MAP-74158

RNA Polymerase III Transcription

7 of 24

2.47

6.21

1.98e-13

MAP-74160

Gene expression (Transcription)

8 of 540

1.17

1.45

9.18e-07

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF03404

Mo-co oxidoreductase dimerisation domain

2 of 4

2.7

1.03

0.0135

PF00174

Oxidoreductase molybdopterin binding domain

2 of 4

2.7

1.03

0.0135

PF00970

Oxidoreductase FAD-binding domain

2 of 7

2.46

1.02

0.0135

PF00175

Oxidoreductase NAD-binding domain

2 of 15

2.13

0.82

0.0304

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR036374

Oxidoreductase, molybdopterin-binding domain superfamily

2 of 4

2.7

0.79

0.0374

IPR008335

Eukaryotic molybdopterin oxidoreductase

2 of 4

2.7

0.79

0.0374

IPR005066

Moybdenum cofactor oxidoreductase, dimerisation

2 of 4

2.7

0.79

0.0374

IPR000572

Oxidoreductase, molybdopterin-binding domain

2 of 4

2.7

0.79

0.0374

IPR008333

Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain

2 of 7

2.46

0.78

0.0374

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00384

DNA binding domain with preference for A/T rich regions

2 of 11

2.26

0.9

0.0218

SM01117

Cytochrome b5-like Heme/Steroid binding domain

2 of 24

1.92

0.71

0.0452

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