node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ASNA1 | chiPu_0000413 | A0A401SFZ3 | A0A401RV59 | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | MPN domain-containing protein. | 0.824 |
ASNA1 | chiPu_0003190 | A0A401SFZ3 | A0A401S352 | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | 40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family. | 0.881 |
ASNA1 | chiPu_0007745 | A0A401SFZ3 | A0A401SFW6 | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | Uncharacterized protein. | 0.968 |
ASNA1 | chiPu_0010687 | A0A401SFZ3 | A0A401SPC0 | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | Uncharacterized protein. | 0.881 |
chiPu_0000413 | ASNA1 | A0A401RV59 | A0A401SFZ3 | MPN domain-containing protein. | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | 0.824 |
chiPu_0000413 | chiPu_0001598 | A0A401RV59 | A0A401RYG5 | MPN domain-containing protein. | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. | 0.999 |
chiPu_0000413 | chiPu_0003190 | A0A401RV59 | A0A401S352 | MPN domain-containing protein. | 40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family. | 0.978 |
chiPu_0000413 | chiPu_0007745 | A0A401RV59 | A0A401SFW6 | MPN domain-containing protein. | Uncharacterized protein. | 0.971 |
chiPu_0000413 | chiPu_0010687 | A0A401RV59 | A0A401SPC0 | MPN domain-containing protein. | Uncharacterized protein. | 0.929 |
chiPu_0000413 | chiPu_0016390 | A0A401RV59 | A0A401T5H9 | MPN domain-containing protein. | Uncharacterized protein. | 0.559 |
chiPu_0000413 | chiPu_0016616 | A0A401RV59 | A0A401T652 | MPN domain-containing protein. | AAA domain-containing protein; Belongs to the AAA ATPase family. | 0.999 |
chiPu_0000413 | chiPu_0020504 | A0A401RV59 | A0A401RGE9 | MPN domain-containing protein. | Ubiquitin-like domain-containing protein. | 0.979 |
chiPu_0001598 | chiPu_0000413 | A0A401RYG5 | A0A401RV59 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. | MPN domain-containing protein. | 0.999 |
chiPu_0001598 | chiPu_0003190 | A0A401RYG5 | A0A401S352 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. | 40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family. | 0.966 |
chiPu_0001598 | chiPu_0007745 | A0A401RYG5 | A0A401SFW6 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. | Uncharacterized protein. | 0.977 |
chiPu_0001598 | chiPu_0010687 | A0A401RYG5 | A0A401SPC0 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. | Uncharacterized protein. | 0.966 |
chiPu_0001598 | chiPu_0016616 | A0A401RYG5 | A0A401T652 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. | AAA domain-containing protein; Belongs to the AAA ATPase family. | 0.999 |
chiPu_0001598 | chiPu_0020504 | A0A401RYG5 | A0A401RGE9 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. | Ubiquitin-like domain-containing protein. | 0.982 |
chiPu_0002472 | chiPu_0003190 | A0A401S0Z7 | A0A401S352 | PAW domain-containing protein. | 40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family. | 0.926 |
chiPu_0002472 | chiPu_0007745 | A0A401S0Z7 | A0A401SFW6 | PAW domain-containing protein. | Uncharacterized protein. | 0.986 |