STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
chiPu_0007745Uncharacterized protein. (379 aa)    
Predicted Functional Partners:
chiPu_0002472
PAW domain-containing protein.
    
 0.986
chiPu_0016390
Uncharacterized protein.
   
 0.986
chiPu_0020504
Ubiquitin-like domain-containing protein.
   
 0.985
chiPu_0010687
Uncharacterized protein.
    
 0.980
chiPu_0001598
26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.
    
 0.977
chiPu_0016616
AAA domain-containing protein; Belongs to the AAA ATPase family.
   
 0.975
chiPu_0008137
Uncharacterized protein.
   
 0.972
chiPu_0000413
MPN domain-containing protein.
   
 0.971
chiPu_0003190
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
 0.968
ASNA1
ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]
   
 0.968
Your Current Organism:
Chiloscyllium punctatum
NCBI taxonomy Id: 137246
Other names: C. punctatum, brownbanded bambooshark
Server load: low (26%) [HD]