STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (757 aa)    
Predicted Functional Partners:
chiPu_2000041
Cys_knot domain-containing protein.
   
 0.958
chiPu_0000812
Cys_knot domain-containing protein.
    
 0.945
chiPu_0012664
Cys_knot domain-containing protein.
   
 0.916
chiPu_0010248
Uncharacterized protein.
    
 0.878
chiPu_0016759
Uncharacterized protein.
    
 0.878
chiPu_0016758
Uncharacterized protein.
    
 0.878
chiPu_0002199
Uncharacterized protein.
    
 0.824
chiPu_0009281
Uncharacterized protein.
    
 0.804
chiPu_0002131
Uncharacterized protein.
    
 0.802
chiPu_2000039
Uncharacterized protein.
   
 
 0.770
Your Current Organism:
Chiloscyllium punctatum
NCBI taxonomy Id: 137246
Other names: C. punctatum, brownbanded bambooshark
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.