chiPu_0016449 protein (Chiloscyllium punctatum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Cooccurrence

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[Homology]

Score

chiPu_0016449

Uncharacterized protein; Belongs to the universal ribosomal protein uL22 family. (203 aa)

Predicted Functional Partners:

chiPu_0017284

0.999

chiPu_0020788

0.999

chiPu_0001164

0.999

chiPu_0002961

0.999

chiPu_0003190

0.999

chiPu_0004025

0.999

chiPu_0004059

0.999

chiPu_0004308

0.999

chiPu_0004511

0.999

chiPu_0006246

0.999

Your Current Organism:

Chiloscyllium punctatum

NCBI taxonomy Id: 137246
Other names: C. punctatum, brownbanded bambooshark

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structured XML interaction data, according to the 'PSI-MI' data standard

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
chiPu_0001164	chiPu_0002961	A0A401RX91	A0A401S2J0	Uncharacterized protein.	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	0.995
chiPu_0001164	chiPu_0004025	A0A401RX91	A0A401S5E3	Uncharacterized protein.	Uncharacterized protein.	0.998
chiPu_0001164	chiPu_0004059	A0A401RX91	A0A401S5I9	Uncharacterized protein.	Uncharacterized protein; Belongs to the universal ribosomal protein uS11 family.	0.979
chiPu_0001164	chiPu_0004308	A0A401RX91	A0A401S670	Uncharacterized protein.	Ribosomal_L18e/L15P domain-containing protein.	0.997
chiPu_0001164	chiPu_0004511	A0A401RX91	A0A401S6T6	Uncharacterized protein.	Uncharacterized protein.	0.999
chiPu_0001164	chiPu_0006246	A0A401RX91	A0A401SBT9	Uncharacterized protein.	Uncharacterized protein.	0.997
chiPu_0001164	chiPu_0016449	A0A401RX91	A0A401T5M2	Uncharacterized protein.	Uncharacterized protein; Belongs to the universal ribosomal protein uL22 family.	0.999
chiPu_0001164	chiPu_0017284	A0A401RX91	A0A401REL2	Uncharacterized protein.	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family.	0.997
chiPu_0001164	chiPu_0020788	A0A401RX91	A0A401RJS9	Uncharacterized protein.	Uncharacterized protein.	0.996
chiPu_0002961	chiPu_0001164	A0A401S2J0	A0A401RX91	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	Uncharacterized protein.	0.995
chiPu_0002961	chiPu_0004025	A0A401S2J0	A0A401S5E3	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	Uncharacterized protein.	0.999
chiPu_0002961	chiPu_0004059	A0A401S2J0	A0A401S5I9	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	Uncharacterized protein; Belongs to the universal ribosomal protein uS11 family.	0.999
chiPu_0002961	chiPu_0004308	A0A401S2J0	A0A401S670	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	Ribosomal_L18e/L15P domain-containing protein.	0.999
chiPu_0002961	chiPu_0004511	A0A401S2J0	A0A401S6T6	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	Uncharacterized protein.	0.999
chiPu_0002961	chiPu_0006246	A0A401S2J0	A0A401SBT9	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	Uncharacterized protein.	0.999
chiPu_0002961	chiPu_0016449	A0A401S2J0	A0A401T5M2	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	Uncharacterized protein; Belongs to the universal ribosomal protein uL22 family.	0.999
chiPu_0002961	chiPu_0017284	A0A401S2J0	A0A401REL2	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family.	0.999
chiPu_0002961	chiPu_0020788	A0A401S2J0	A0A401RJS9	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	Uncharacterized protein.	0.999
chiPu_0003190	chiPu_0004059	A0A401S352	A0A401S5I9	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	Uncharacterized protein; Belongs to the universal ribosomal protein uS11 family.	0.999
chiPu_0003190	chiPu_0004308	A0A401S352	A0A401S670	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	Ribosomal_L18e/L15P domain-containing protein.	0.999

page 1 of 5

Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

29

PPI enrichment p-value:

3.91e-06

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006351

Transcription, DNA-templated

4 of 10

1.72

1.59

0.00034

GO:0016070

RNA metabolic process

7 of 91

1.01

0.91

0.00034

GO:0010467

Gene expression

9 of 147

0.91

0.87

5.22e-05

GO:0006353

DNA-templated transcription, termination

2 of 4

1.82

0.8

0.0287

GO:0034654

Nucleobase-containing compound biosynthetic process

5 of 88

0.88

0.58

0.0133

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016779

Nucleotidyltransferase activity

4 of 28

1.28

0.88

0.0066

GO:0003723

RNA binding

6 of 83

0.98

0.75

0.0030

GO:0003676

Nucleic acid binding

9 of 230

0.71

0.57

0.0011

GO:1901363

Heterocyclic compound binding

10 of 446

0.47

0.36

0.0066

GO:0097159

Organic cyclic compound binding

10 of 446

0.47

0.36

0.0066

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:285

Ribosomal small subunit biogenesis, and tRNA pseudouridine synthesis

3 of 5

1.9

1.47

0.0011

CL:110

Ribosome, and Protein transport

7 of 96

0.98

0.9

0.00027

CL:104

Gene expression, and Protein folding

9 of 192

0.79

0.7

0.00019

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03018

RNA degradation

4 of 14

1.58

1.44

0.00047

map03020

RNA polymerase

2 of 4

1.82

0.76

0.0353

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0806

Transcription termination

2 of 3

1.94

0.83

0.0264

KW-0240

DNA-directed RNA polymerase

2 of 4

1.82

0.82

0.0264

KW-0548

Nucleotidyltransferase

3 of 20

1.3

0.7

0.0264

KW-0694

RNA-binding

5 of 63

1.02

0.68

0.0109

KW-0804

Transcription

4 of 45

1.07

0.62

0.0241

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00322

K homology RNA-binding domain

2 of 4

1.82

0.73

0.0402

SM00316

Ribosomal protein S1-like RNA-binding domain

2 of 4

1.82

0.73

0.0402

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