STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
chiPu_0025035Uncharacterized protein. (37 aa)    
Predicted Functional Partners:
chiPu_0017661
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]
    
  0.733
chiPu_0018153
ThiF domain-containing protein.
    
  0.733
chiPu_0008756
E2_bind domain-containing protein.
    
  0.733
chiPu_0008537
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
   
 
 0.730
chiPu_0013624
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
     
 0.710
chiPu_0003052
Uncharacterized protein; Belongs to the ubiquitin-conjugating enzyme family.
     
 0.709
chiPu_0009213
UBIQUITIN_CONJUGAT_2 domain-containing protein.
     
 0.698
chiPu_0004768
UBIQUITIN_CONJUGAT_2 domain-containing protein.
     
 0.679
chiPu_0019959
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
     
 0.668
chiPu_0006843
Ubiquitin-like domain-containing protein.
    
  0.662
Your Current Organism:
Chiloscyllium punctatum
NCBI taxonomy Id: 137246
Other names: C. punctatum, brownbanded bambooshark
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.