chiPu_0028454 protein (Chiloscyllium punctatum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

chiPu_0028454

Uncharacterized protein. (40 aa)

Predicted Functional Partners:

chiPu_0008381

0.998

chiPu_0033351

0.873

chiPu_0018794

0.829

chiPu_0018795

0.829

chiPu_0019707

0.829

chiPu_0006138

0.829

chiPu_0008657

0.829

chiPu_0009329

0.829

chiPu_0010256

0.829

chiPu_0012542

0.829

Your Current Organism:

Chiloscyllium punctatum

NCBI taxonomy Id: 137246
Other names: C. punctatum, brownbanded bambooshark

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
chiPu_0006138	chiPu_0008381	A0A401SBE1	A0A401SHQ1	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Uncharacterized protein.	0.998
chiPu_0006138	chiPu_0028454	A0A401SBE1	A0A401TPC4	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Uncharacterized protein.	0.829
chiPu_0008381	chiPu_0006138	A0A401SHQ1	A0A401SBE1	Uncharacterized protein.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.998
chiPu_0008381	chiPu_0008657	A0A401SHQ1	A0A401SIH2	Uncharacterized protein.	Tubulin domain-containing protein; Belongs to the tubulin family.	0.998
chiPu_0008381	chiPu_0009329	A0A401SHQ1	A0A401SKG7	Uncharacterized protein.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.998
chiPu_0008381	chiPu_0010256	A0A401SHQ1	A0A401SN29	Uncharacterized protein.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.998
chiPu_0008381	chiPu_0012542	A0A401SHQ1	A0A401SUK0	Uncharacterized protein.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	0.998
chiPu_0008381	chiPu_0018794	A0A401SHQ1	A0A401RPV8	Uncharacterized protein.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.998
chiPu_0008381	chiPu_0018795	A0A401SHQ1	A0A401RR89	Uncharacterized protein.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	0.998
chiPu_0008381	chiPu_0019707	A0A401SHQ1	A0A401RSX5	Uncharacterized protein.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	0.998
chiPu_0008381	chiPu_0028454	A0A401SHQ1	A0A401TPC4	Uncharacterized protein.	Uncharacterized protein.	0.998
chiPu_0008381	chiPu_0033351	A0A401SHQ1	A0A401U346	Uncharacterized protein.	Tubulin domain-containing protein.	0.998
chiPu_0008657	chiPu_0008381	A0A401SIH2	A0A401SHQ1	Tubulin domain-containing protein; Belongs to the tubulin family.	Uncharacterized protein.	0.998
chiPu_0008657	chiPu_0028454	A0A401SIH2	A0A401TPC4	Tubulin domain-containing protein; Belongs to the tubulin family.	Uncharacterized protein.	0.829
chiPu_0008657	chiPu_0033351	A0A401SIH2	A0A401U346	Tubulin domain-containing protein; Belongs to the tubulin family.	Tubulin domain-containing protein.	0.494
chiPu_0009329	chiPu_0008381	A0A401SKG7	A0A401SHQ1	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Uncharacterized protein.	0.998
chiPu_0009329	chiPu_0028454	A0A401SKG7	A0A401TPC4	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Uncharacterized protein.	0.829
chiPu_0010256	chiPu_0008381	A0A401SN29	A0A401SHQ1	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Uncharacterized protein.	0.998
chiPu_0010256	chiPu_0028454	A0A401SN29	A0A401TPC4	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	Uncharacterized protein.	0.829
chiPu_0012542	chiPu_0008381	A0A401SUK0	A0A401SHQ1	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.	Uncharacterized protein.	0.998

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Network Stats

number of nodes:

11

number of edges:

53

average node degree:

9.64

avg. local clustering coefficient:

0.968

expected number of edges:

16

PPI enrichment p-value:

1.31e-13

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0032981

Mitochondrial respiratory chain complex I assembly

9 of 42

2.51

8.2

5.64e-18

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005743

Mitochondrial inner membrane

6 of 323

1.45

1.78

8.07e-06

GO:0031966

Mitochondrial membrane

7 of 494

1.33

1.64

4.26e-06

GO:0005739

Mitochondrion

10 of 1190

1.1

1.41

5.05e-08

GO:0005747

Mitochondrial respiratory chain complex I

2 of 36

1.92

0.74

0.0407

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:9010

NADH dehydrogenase complex assembly

9 of 12

3.05

11.37

2.23e-22

CL:8839

Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.

10 of 100

2.18

7.13

2.14e-18

CL:9013

Mixed, incl. MTH938-like superfamily, and Squalene/phytoene synthase

5 of 6

3.1

5.88

1.49e-11

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-6799198

Complex I biogenesis

9 of 48

2.45

8.13

3.08e-18

MAP-611105

Respiratory electron transport

9 of 91

2.17

6.45

3.24e-16

MAP-163200

Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.

9 of 112

2.08

5.93

1.28e-15

MAP-1428517

The citric acid (TCA) cycle and respiratory electron transport

9 of 168

1.91

4.87

3.23e-14

MAP-1430728

Metabolism

9 of 2060

0.82

0.75

0.00010

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005743

Mitochondrial inner membrane

5 of 165

1.66

1.88

3.58e-05

GOCC:0005739

Mitochondrion

8 of 742

1.21

1.45

3.73e-06

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