STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDZ62104.1Hydroxymethylpyrimidine kinase. (269 aa)    
Predicted Functional Partners:
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
 0.999
SDZ64370.1
Thiaminase.
 
 0.997
SDZ62107.1
Thiamine-phosphate pyrophosphorylase.
 
 
 0.996
thiG
Thiazole-phosphate synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
  
 0.988
SDZ62115.1
Sulfur carrier protein ThiS.
  
 
  0.978
SDZ62122.1
Glycine oxidase.
 
  
 0.909
SDZ64374.1
Thiaminase (transcriptional activator TenA); Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4- amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2- methylpyrimidine (HMP); Belongs to the TenA family.
  
 
 0.906
SDZ62129.1
Putative hydroxymethylpyrimidine transporter CytX.
  
  
 0.866
thiL
Thiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
    
 0.826
SDY68337.1
Adenylyltransferase and sulfurtransferase.
 
  
 0.737
Your Current Organism:
Asanoa ishikariensis
NCBI taxonomy Id: 137265
Other names: A. ishikariensis, Asanoa ishikariensis Lee and Hah 2002, Catellatispora ishikariense, Catellatospora ishikariense, DSM 44718, IFO 14551, IMSNU 22004, JCM 11895, NBRC 14551, strain 6432-C
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