Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MIS12Uncharacterized protein. (210 aa)    
Predicted Functional Partners:
DSN1
DSN1 component of MIS12 kinetochore complex.
    
 0.986
NDC80
NDC80 kinetochore complex component.
   
 0.980
NUF2
NUF2 component of NDC80 kinetochore complex.
   
 0.975
SPC25
SPC25 component of NDC80 kinetochore complex.
    
 0.971
PMF1
Polyamine modulated factor 1.
    
 0.964
BUB1B
BUB1 N-terminal domain-containing protein.
    
 0.952
KNL1
Kinetochore scaffold 1.
   
 0.952
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
    
 0.943
ZWINT
Uncharacterized protein.
    
 0.920
FGA
Fibrinogen alpha chain.
    
   0.858
Your Current Organism:
Pelodiscus sinensis
NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.