Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
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[Homology]
Score
LOC102449374H15 domain-containing protein. (214 aa)    
Predicted Functional Partners:
H2AZ2
Histone H2A; Belongs to the histone H2A family.
   
 
 0.606
H2AZ1
Histone H2A; Belongs to the histone H2A family.
   
 
 0.606
NOC2L
NOC2 like nucleolar associated transcriptional repressor.
    
   0.509
ACTL6B
Actin like 6B; Belongs to the actin family.
    
 
 0.485
ACTL6A
Actin like 6A; Belongs to the actin family.
    
 
 0.485
RPL26
Ribosomal protein L26.
    
   0.460
H1-10
H1 histone family member X.
   
 
 0.437
SUPT16H
SPT16 homolog, facilitates chromatin remodeling subunit.
   
 
 0.432
LOC106732714
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 0.413
K7EXN6_PELSI
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 0.413
Your Current Organism:
Pelodiscus sinensis
NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38
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