Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RHOHRas homolog family member H. (191 aa)    
Predicted Functional Partners:
RHOB
Ras homolog family member B.
  
0.941
ITSN2
Intersectin 2.
    
 0.842
PAK2
Non-specific serine/threonine protein kinase.
    
 0.810
ARHGDIB
Rho GDP dissociation inhibitor beta.
   
 0.768
ARHGDIA
Rho GDP dissociation inhibitor alpha.
   
 0.768
ITSN1
Intersectin 1.
    
 0.744
ZAP70
Tyrosine-protein kinase.
   
 0.728
PAK6
Non-specific serine/threonine protein kinase.
    
 0.706
MRPS5
Mitochondrial ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family.
   
 
 0.703
ROCK1
Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
   
 0.700
Your Current Organism:
Pelodiscus sinensis
NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38
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