| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACMSD | SENP8 | ENSPSIP00000009800 | ENSPSIP00000001705 | 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. | SUMO peptidase family member, NEDD8 specific. | 0.841 |
| ACO1 | ACO2 | ENSPSIP00000009155 | ENSPSIP00000008041 | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. | 0.930 |
| ACO1 | CUL1 | ENSPSIP00000009155 | ENSPSIP00000017614 | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | Cullin 1; Belongs to the cullin family. | 0.569 |
| ACO1 | IREB2 | ENSPSIP00000009155 | ENSPSIP00000010930 | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | Iron responsive element binding protein 2; Belongs to the aconitase/IPM isomerase family. | 0.556 |
| ACO1 | SENP8 | ENSPSIP00000009155 | ENSPSIP00000001705 | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | SUMO peptidase family member, NEDD8 specific. | 0.808 |
| ACO2 | ACO1 | ENSPSIP00000008041 | ENSPSIP00000009155 | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | 0.930 |
| ACO2 | SENP8 | ENSPSIP00000008041 | ENSPSIP00000001705 | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. | SUMO peptidase family member, NEDD8 specific. | 0.808 |
| CUL1 | ACO1 | ENSPSIP00000017614 | ENSPSIP00000009155 | Cullin 1; Belongs to the cullin family. | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | 0.569 |
| CUL1 | IREB2 | ENSPSIP00000017614 | ENSPSIP00000010930 | Cullin 1; Belongs to the cullin family. | Iron responsive element binding protein 2; Belongs to the aconitase/IPM isomerase family. | 0.632 |
| CUL1 | SENP8 | ENSPSIP00000017614 | ENSPSIP00000001705 | Cullin 1; Belongs to the cullin family. | SUMO peptidase family member, NEDD8 specific. | 0.916 |
| IREB2 | ACO1 | ENSPSIP00000010930 | ENSPSIP00000009155 | Iron responsive element binding protein 2; Belongs to the aconitase/IPM isomerase family. | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | 0.556 |
| IREB2 | CUL1 | ENSPSIP00000010930 | ENSPSIP00000017614 | Iron responsive element binding protein 2; Belongs to the aconitase/IPM isomerase family. | Cullin 1; Belongs to the cullin family. | 0.632 |
| IREB2 | SENP8 | ENSPSIP00000010930 | ENSPSIP00000001705 | Iron responsive element binding protein 2; Belongs to the aconitase/IPM isomerase family. | SUMO peptidase family member, NEDD8 specific. | 0.808 |
| PIGL | SENP8 | ENSPSIP00000020455 | ENSPSIP00000001705 | Phosphatidylinositol glycan anchor biosynthesis class L. | SUMO peptidase family member, NEDD8 specific. | 0.839 |
| PSTPIP2 | SENP8 | ENSPSIP00000011063 | ENSPSIP00000001705 | Proline-serine-threonine phosphatase interacting protein 2. | SUMO peptidase family member, NEDD8 specific. | 0.790 |
| PSTPIP2 | TRMT5 | ENSPSIP00000011063 | ENSPSIP00000015845 | Proline-serine-threonine phosphatase interacting protein 2. | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. | 0.790 |
| SENP8 | ACMSD | ENSPSIP00000001705 | ENSPSIP00000009800 | SUMO peptidase family member, NEDD8 specific. | 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. | 0.841 |
| SENP8 | ACO1 | ENSPSIP00000001705 | ENSPSIP00000009155 | SUMO peptidase family member, NEDD8 specific. | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | 0.808 |
| SENP8 | ACO2 | ENSPSIP00000001705 | ENSPSIP00000008041 | SUMO peptidase family member, NEDD8 specific. | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. | 0.808 |
| SENP8 | CUL1 | ENSPSIP00000001705 | ENSPSIP00000017614 | SUMO peptidase family member, NEDD8 specific. | Cullin 1; Belongs to the cullin family. | 0.916 |