Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SOCS5Suppressor of cytokine signaling 5. (535 aa)    
Predicted Functional Partners:
CUL5
Cullin 5; Belongs to the cullin family.
   
 0.939
ELOC
Elongin C; Belongs to the SKP1 family.
    
 0.921
RNF7
Ring finger protein 7.
   
 0.819
CISH
Cytokine inducible SH2 containing protein.
     
0.783
JAK1
Tyrosine-protein kinase.
    
 0.781
SOCS2
Suppressor of cytokine signaling 2.
     
0.736
SOCS1
Suppressor of cytokine signaling 1.
     
0.696
JAK3
Tyrosine-protein kinase.
    
 0.673
JAK2
Tyrosine-protein kinase.
    
 0.673
PIK3R5
Phosphoinositide-3-kinase regulatory subunit 5.
  
  
 0.625
Your Current Organism:
Pelodiscus sinensis
NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38
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